Clinical Reasoning: A 55-Year-Old Woman With Painless Hand Weakness and Atrophy.

Neurology

From the Neurological Institute (H.T., B.K.), University Hospitals, Cleveland Medical Center; and Department of Neurology (H.T., B.K.), Case Western Reserve University School of Medicine, Cleveland, OH.

Published: July 2024

AI Article Synopsis

  • - A 55-year-old woman experienced worsening weakness and muscle atrophy in her right hand, specifically affecting the thenar muscles, with no sensory issues noted.
  • - She had a background of carpal tunnel syndrome and previously had surgery for it, prompting an exploration of her hand weakness's underlying causes.
  • - The case highlights the importance of understanding muscle innervation, provides a structured way to diagnose this hand weakness, and offers a range of potential diagnoses for similar clinical presentations.

Article Abstract

Hand weakness is a frequent chief concern in neurology practice. We report a case of a 55-year-old woman presenting with a chronic, gradually worsening right hand weakness and atrophy, selectively affecting the thenar muscles, without any sensory symptoms. She had a history of carpal tunnel syndrome and previously underwent surgical carpal tunnel release. This case delves into the differential diagnosis of hand weakness and atrophy, emphasizing the significance of myotomal innervation in intrinsic hand muscles. Furthermore, it outlines a systematic approach to diagnosing an uncommon cause for a common clinical presentation, offering a comprehensive differential diagnosis, and exploring various possible causes.

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Source
http://dx.doi.org/10.1212/WNL.0000000000209561DOI Listing

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