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Reversible right bundle branch block caused by spasm of the anterior septal branch: case report.
BMC Cardiovasc Disord
December 2024
Departmentof Cardiology, Wuhan Asia Heart Hospital, Wuhan, China.
Background: Coronary Artery Spasm (CAS) often presents in the epicardial coronary arteries. The anterior septal branch is distributed within the myocardium, and occurrences of spasms are rare. Currently, there is no available literature on this topic, and the onset of symptoms remains elusive, potentially leading to misdiagnosis.
View Article and Find Full Text PDFEffects of 12-Week Moderate-Intensity Versus High-Intensity Water-Aerobic Training on Physical Fitness, Cardiovascular Health, and Well-Being in Adults and Older Adults: A Pragmatic Randomized Controlled Trial.
Health Sci Rep
December 2024
Department of Sport Sciences University of Beira Interior Covilhã Portugal.
Background And Aims: The current study aimed to compare the effects of 12 weeks of moderate versus high-intensity water aerobics on muscle strength, body composition, lipid profile, blood pressure, and quality of life in both adults and older adults.
Methods: Twenty-one women (65.19 ± 9.
Calcific aortic stenosis: omics-based target discovery and therapy development.
Eur Heart J
December 2024
Center for Interdisciplinary Cardiovascular Sciences, Brigham and Women's Hospital, Harvard Medical School, 3 Blackfan Street, 17th Floor, Boston, MA 02115, USA.
Calcific aortic valve disease (CAVD) resulting in aortic stenosis (AS) is the most common form of valvular heart disease, affecting 2% of those over age 65. Those who develop symptomatic severe AS have an average further lifespan of <2 years without valve replacement, and three-quarters of these patients will develop heart failure, undergo valve replacement, or die within 5 years. There are no approved pharmaceutical therapies for AS, due primarily to a limited understanding of the molecular mechanisms that direct CAVD progression in the complex haemodynamic environment.
View Article and Find Full Text PDFPhysical Fitness, Executive Functions, and Academic Performance in Children and Youth: A Cross-Sectional Study.
Behav Sci (Basel)
November 2024
Exercise Neuroscience Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro 22290-140, RJ, Brazil.
The aim of this cross-sectional study was to investigate the relationship between physical fitness, executive function, and academic performance in children and adolescents. A total of 131 students (49% female) aged 10-15 years from a public school in Rio de Janeiro were assessed in executive functions (hearts and flowers, Corsi's block, and digit span tasks), academic performance (Portuguese, reading, math, and overall school grade), physical tests (touch test disc, agility, lower limb and upper limb explosive strength), and anthropometric measurements. Regression results showed that the composite of sports-related fitness measures was the best predictor of executive functions (β = 0.
View Article and Find Full Text PDFNeuroprotective Potential of Nitroglycerin in Ischemic Stroke: Insights into Neural Glucose Metabolism and Endoplasmic Reticulum Stress Inhibition.
J Am Heart Assoc
December 2024
Neuroscience Institute, Beijing Luhe Hospital Capital Medical University Beijing China.
Background: Glyceryl trinitrate (GTN), also known as nitroglycerin, is predominantly recognized as a vasodilator for ischemic heart disease, and its potential neuroprotective properties in acute ischemic stroke remain under exploration. We sought to discover the therapeutic advantages and mechanisms of post-recanalization GTN administration in acute ischemic stroke.
Methods And Results: A total of 118 male Sprague-Dawley rats were divided into groups: sham, transient/permanent middle cerebral artery occlusion (MCAO) with or without GTN treatment, and transient/permanent MCAO treated with both GTN and KT5823, an inhibitor of PKG.
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