AI Article Synopsis
- Researchers designed nanoparticles that become active drugs when they dissolve inside cells, specifically targeting cancer cells using hydrogen peroxide.
- The study aims to clarify how these nanoparticles release their drugs when they interact with hydrogen peroxide in cancerous environments.
- It includes experiments that simulate cancer cell conditions to measure and understand the speed and efficiency of the drug release process.
Article Abstract
We developed prodrug nanoparticles that release drugs through intracellular dissolution and a cancer-specific hydrogen peroxide response. To reveal the unclear mechanism regarding drug release from nanoparticles by reacting with hydrogen peroxide in cancer cells, this study demonstrates the evaluation of drug release kinetics under conditions simulated in cancer cells.
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| http://dx.doi.org/10.1039/d4cc02252a | DOI Listing |
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