Eight furostanol glycosides including five undescribed compounds, named tribufurostanosides A-E (1-5), and three known ones (6-8) were isolated from the fruits of Tribulus terrestris L. Their chemical structures were determined by the IR, HR-ESI-MS, 1D-, and 2D-NMR spectra. Furostanols 1-8 significantly inhibited nitric oxide production in LPS activated RAW 264.7 cells with IC values ranging from 14.2 to 64.7 μM, compared to that of the positive control compound, dexamethazone (IC 13.6 μM).
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| http://dx.doi.org/10.1002/cbdv.202401273 | DOI Listing |
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