An oxidative free-radical C(sp)-H bond chlorination strategy of enaminones has been developed by using LiCl as a chlorinating reagent and KSO as an oxidant. This transformation provides a new and straightforward synthetic methodology to afford highly functionalized α-chlorinated enaminones with a -configuration in good to excellent yields.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.4c00456 | DOI Listing |
Publication Analysis
Top Keywords
oxidative free-radical
8
free-radical csp-h
8
csp-h bond
8
bond chlorination
8
highly functionalized
8
functionalized α-chlorinated
8
α-chlorinated enaminones
8
enaminones
4
chlorination enaminones
4
enaminones licl
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!