AI Article Synopsis
- Endocrine disrupting chemicals (EDCs) and carcinogens have long been recognized for their ability to interfere with hormonal signals in the body, raising significant health concerns.
- Researchers have extensively studied how these chemicals affect various human organs and their potential to be cancer-causing agents.
- The review highlights the identification of hazards linked to EDCs, their exposure routes, carcinogenic properties, and outlines existing research gaps and limitations in detection methods.
Article Abstract
Endocrine disrupting chemicals or carcinogens have been known for decades for their endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they have been included in the top priority toxicants and persistent organic pollutants. Therefore, researchers have been working for a long time to understand their mechanisms of interaction in different human organs. Several reports are available about the carcinogen potential of these chemicals. The presented review is an endeavor to understand the hazard identification associated with endocrine disrupting carcinogens in relation to the human body. The paper discusses the major endocrine disrupting carcinogens and their potency for carcinogenesis. It discusses human exposure, route of entry, carcinogenicity and mechanisms. In addition, the paper discusses the research gaps and bottlenecks associated with the research. Moreover, it discusses the limitations associated with the analytical techniques for detection of endocrine disrupting carcinogens.
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| http://dx.doi.org/10.1016/j.etap.2024.104480 | DOI Listing |
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