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Rnalib: a Python library for custom transcriptomics analyses.
Bioinformatics
December 2024
Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, A-1030, Austria.
Motivation: The efficient and reproducible analysis of high-throughput sequencing datasets necessitates the development of methodical and robust computational pipelines that integrate established and bespoke bioinformatics analysis tools, often written in high-level programming languages such as Python. Despite the increasing availability of programming libraries for genomics, there is a noticeable lack of tools specifically focused on transcriptomics. Key tasks in this area include the association of gene features (e.
View Article and Find Full Text PDFThe Precise Synthesis of Ultradense Bottlebrush Polymers Unearths Unique Trends in Lyotropic Ordering.
J Am Chem Soc
December 2024
Department of Chemistry at Brown University, 324 Brook Street, Providence, Rhode Island 02912, United States.
Biomacromolecular networks with multiscale fibrillar structures are characterized by exceptional mechanical properties, making them attractive architectures for synthetic materials. However, there is a dearth of synthetic polymeric building blocks capable of forming similarly structured networks. Bottlebrush polymers (BBPs) are anisotropic graft polymers with the potential to mimic and replace biomacromolecules such as tropocollagen for the fabrication of synthetic fibrillar networks; however, a longstanding limitation of BBPs has been the lack of rigidity necessary to access the lyotropic ordering that underpins the formation of collagenous networks.
View Article and Find Full Text PDFAccess to maternity waiting home services and its determinants among women in Ethiopia: systematic reviews and meta-analysis.
Front Glob Womens Health
December 2024
Department of Preventive Medicine and Public Health, Food Science, Toxicology, and Legal Medicine, University of Valencia, Valencia, Spain.
Introduction: Globally, maternal mortality is a major public health problem mainly due to a lack of access to skilled care during childbirth. Maternity waiting homes (MWHs) play a critical role in accessing emergency obstetric care for pregnant women during childbirth. However, available studies show inconsistent findings about women's utilization of maternity waiting homes.
View Article and Find Full Text PDFFamily planning utilization among postpartum women in the Bule Hora District, southern Ethiopia.
Front Glob Womens Health
December 2024
Department of Midwifery, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Background: Contraception use remains low in Ethiopia, particularly within the first year after childbirth. While some women might have medical conditions that limit their contraceptive options, the primary obstacle to wider family planning adoption is not a specific health problem. Instead, it is the lack of equitable access to high-quality family planning services.
View Article and Find Full Text PDFEnhancing strategic decision-making in built asset management through BIM-Enabled asset information modelling (AIM) for public buildings in Ethiopia: A fuzzy-AHP analysis.
Heliyon
December 2024
Chair of Construction Management, Ethiopian Institute of Architecture Building Construction and City Development (EiABC), Addis Ababa University, Addis Ababa, Ethiopia.
BIM-Enabled Asset Information Modelling (AIM) entails incorporating extensive data, known as big data, into digital platforms for informed decision-making. However, the lack of accurate and reliable data and the immaturity of BIM integration in existing buildings lead to operational phase performance inefficiencies due to inadequate data access. A strategic approach using BIM-enabled AIM is proposed to address these challenges, with the goal of enhancing data accessibility and adequacy for the operational team's performance.
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