AI Article Synopsis
- Atrial fibrillation (AF) is common, but there’s a lack of substantial data to help doctors choose the right rate control medications (RCM) for patients.
- Using a large nationwide database, researchers analyzed prescribing habits among 135,927 AF patients and found that beta blockers (BB) were the most frequently prescribed (44.6%), followed by calcium channel blockers (CCB) (14.0%) and digoxin (8.6%).
- The study noted differences in gender and medication type: BBs were more commonly prescribed to males, while CCBs were prescribed less frequently to males, and highlighted the need for further randomized trials to better determine the best RCM options.
Article Abstract
Atrial fibrillation (AF) is common, but there are limited data to guide selection of rate control medications (RCM). Reasons for selection are multivariable, and the impact on outcomes is unknown. We investigated prescribing patterns of RCM among patients with AF. Using a nationwide database, we identified 135,927 patients with AF. We stratified by baseline presence of heart failure with reduced ejection fraction (HFrEF) and examined prescription rates of RCM as a function of clinical variables. We also evaluated associations with clinical outcomes. Beta blockers (BB) were most commonly prescribed (44.6%), then calcium channel blockers (CCB) (14.0%) and digoxin (8.6%). Patients prescribed BB were more likely male (45.6% vs 43.4%, p < 0.0001), patients prescribed CCB were less likely male (12.0% vs 16.3%, p < 0.0001). There were higher rates of HF hospitalization (HFH) among females and those with Medicaid. Randomized trials are needed to define optimal choice of RCM.
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| http://dx.doi.org/10.1016/j.cpcardiol.2024.102669 | DOI Listing |
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