AI Article Synopsis
- This review discusses recent methods for creating quinoxaline derivatives and their potential to trigger cell death (apoptosis) in cancer cells.
- Quinoxaline derivatives have shown promising anticancer effects across various cancer cell lines, outperforming standard reference drugs by inhibiting specific targets.
- The article highlights key quinoxaline derivatives, their synthesis methods, and their effectiveness against different molecular targets, suggesting their viability as targeted cancer treatments.
Article Abstract
The current review outlines all possible recent synthetic platforms to quinoxaline derivatives and the potent stimulated apoptosis mechanisms targeted by anticancer therapies. The currently reported results disclosed that quinoxaline derivatives had promising anticancer potencies against a wide array of cancer cell lines, better than the reference drugs, through target inhibition. This review summarizes some potent quinoxaline derivatives with their synthesis strategies and their potential activities against various molecular targets. Quinoxalines can be considered an important scaffold for apoptosis inducers in cancer cells through inhibiting some molecular targets, so they can be further developed as target-oriented chemotherapeutics.
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| http://dx.doi.org/10.1002/ardp.202400225 | DOI Listing |
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