Purpose: Since the introduction of the Exeter stem for clinical use in Japan in 1996, the number of stems used has continued to rise owing to its favorable results. We investigated the outcomes of patients who had previously undergone total hip arthroplasty with the Exeter stem in Japan with a 10-year + follow-up period.
Methods: This retrospective cohort study used clinical and radiographic data of 682 cases of primary total hip arthroplasty performed using the Exeter stem.
Results: The mean postoperative follow-up period was 13.3 years. Femoral-side revision was required in 14 hips, with no cases of aseptic stem loosening-associated revision observed. Kaplan-Meier survival analysis predicted 97.3% 15-year survival when revision for any reason was used as the endpoint.
Conclusion: The obtained findings suggested the excellent long-term stability of the Exeter stem for primary total hip arthroplasty in Japan.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377650 | PMC |
| http://dx.doi.org/10.1007/s00590-024-04001-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons.
BMC Med Genomics
January 2025
Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.
Amyotrophic lateral sclerosis (ALS) lacks a specific biomarker, but is defined by relatively selective toxicity to motor neurons (MN). As others have highlighted, this offers an opportunity to develop a sensitive and specific biomarker based on detection of DNA released from dying MN within accessible biofluids. Here we have performed whole genome bisulfite sequencing (WGBS) of iPSC-derived MN from neurologically normal individuals.
View Article and Find Full Text PDFMetallosis, Trunnionosis, and Head-stem Dissociation of the Exeter v40 Stem in a Metal-on-Metal Hip: A Unique Case.
J Orthop Case Rep
January 2025
Department of Trauma and Orthopaedic Surgeon, Cork University Hospital, Ireland.
Introduction: In this article, we report a unique case of head-stem dissociation in a metal-on-metal total hip replacement which utilized an Exeter stem. Although metallosis and pseudotumor formation are well recognized complications of metal-on-metal hip replacements, head-stem dissociations are rare with few being reported in literature. To the best of our knowledge, this case report is the first to report this occurrence in an Exeter stem.
View Article and Find Full Text PDFA systematic review of short- compared with standard-length Exeter stems in primary total hip arthroplasty.
Bone Joint J
January 2025
Grampian Orthopaedics, Aberdeen Royal Infirmary, Aberdeen, UK.
Aims: The Exeter femoral stem has a cemented, polished taper-slip design, and an excellent track record. The current range includes short-length options for various offsets, but less is known about the performance of these stems. The aim of this study was to compare the survival of short-length stems with standard-length Exeter stems.
View Article and Find Full Text PDFOncogenic PIK3CA corrupts growth factor signaling specificity.
Mol Syst Biol
December 2024
Cell Signaling Laboratory, Department of Oncology, University College London Cancer Institute Paul O'Gorman Building, University College London, London, WC1E 6BT, UK.
Technical limitations have prevented understanding of how growth factor signals are encoded in distinct activity patterns of the phosphoinositide 3-kinase (PI3K)/AKT pathway, and how this is altered by oncogenic pathway mutations. We introduce a kinetic, single-cell framework for precise calculations of PI3K-specific information transfer for different growth factors. This features live-cell imaging of PI3K/AKT activity reporters and multiplexed CyTOF measurements of PI3K/AKT and RAS/ERK signaling markers over time.
View Article and Find Full Text PDFOverexpression and alternative splicing of the glutamate-gated chloride channel are associated with emamectin benzoate resistance in the rice stem borer, Chilo suppressalis Walker (Lepidoptera: Crambidae).
Pest Manag Sci
December 2024
College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Centre of Green Pesticide Invention and Application, Nanjing, China.
Background: The rice stem borer, Chilo suppressalis Walker (Lepidoptera: Crambidae), is a damaging pest of rice worldwide. Following the evolution of C. suppressalis resistance to diamide and abamectin insecticides, emamectin benzoate (EB) became a key insecticide for the control of this species in China.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!