AI Article Synopsis
- The study aimed to examine if the season during radiotherapy affects the occurrence of grade ≥2 dermatitis in breast cancer patients.
- It involved a retrospective analysis of 327 patients and considered different seasonal periods and treatment factors but found no significant associations.
- The conclusion indicates that the season doesn't affect dermatitis rates, suggesting that it's not a key factor for future clinical trials.
Article Abstract
Background/aim: We investigated grade ≥2 dermatitis in patients irradiated for breast cancer. This study evaluated associations between dermatitis and the season during which radiotherapy took place.
Patients And Methods: Associations between the season and grade ≥2 dermatitis were retrospectively evaluated in 327 breast cancer patients. Seasons were March to May (spring), June to August (summer), September to November (autumn), and December to February (winter). Subgroup analyses were performed considering fractionation, radiation technique, treatment volume, radiation boost, and deep-inspiration breath-hold technique. Furthermore, warmer and cooler months were compared.
Results: The season had no significant impact on the rate of grade ≥2 dermatitis in the entire cohort (p=0.63) nor in the subgroup analyses (p-values between 0.17 and 0.82). No significant difference in rate was found between warm and cool months.
Conclusion: Grade ≥2 dermatitis was not associated with the season during which radiotherapy was performed. This factor may not be important for stratification in prospective trials.
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| http://dx.doi.org/10.21873/anticanres.17067 | DOI Listing |
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