Rapid response on facial psoriasis to bimekizumab: case series.

Drugs Context

Dermatology Unit "Daniele Innocenzi", ASL Latina, Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Italy.

Published: May 2024

AI Article Synopsis

  • * Biologics, especially IL-17 and IL-23 inhibitors, have been effective in treating psoriatic lesions, including challenging locations.
  • * This case series presents the first real-life data showing the quick and successful treatment of facial psoriasis in six patients using bimekizumab, even though previous studies didn't specifically address facial lesions.

Article Abstract

Psoriasis is a chronic inflammatory disease that can affect any part of the body but, when it appears in certain areas, like the face, it can have a very significant psychological impact. Biologics, in particular IL-17 and IL-23 drug inhibitors, have shown relevant clinical efficacy in the management of psoriatic lesions in difficult-to-treat areas. In post hoc analysis of phase III trials in plaque psoriasis, bimekizumab has shown safety and complete clearance of high-impact areas. However, these studies did not focus on the effect of bimekizumab on facial lesions. Therefore, this case series represents the first clinical real-life experience of rapid and successful management of facial psoriasis with bimekizumab in six patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11139169PMC
http://dx.doi.org/10.7573/dic.2024-1-4DOI Listing

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