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Arthritis alleviation: unveiling the potential in macerated oil. | LitMetric

Arthritis alleviation: unveiling the potential in macerated oil.

Future Sci OA

Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science & Technology, Kattankulathur, 603203, Chengalpattu, Tamil Nadu, India.

Published: May 2024

This study endeavors to explore the anti-arthritic effects of macerated oil derived from the plant's aerial parts. The macerated oil was prepared using maceration in coconut oil, and its phytochemical composition was elucidated using GC-MS. To assess its anti-arthritic activity, studies were conducted using various assays. The macerated oil showed better antioxidant and anti-arthritic potential by - investigations. Molecular docking studies elucidated potential binding interactions between specific constituents of the oil and critical molecular targets implicated in the pathogenesis of arthritis, further substantiating its therapeutic potential. The results demonstrated that macerated oil could ameliorate arthritis severity in a dose-dependent manner.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137774PMC
http://dx.doi.org/10.2144/fsoa-2023-0248DOI Listing

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