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Single-Cell Peptide Profiling to Distinguish Stickleback Ecotypes with Divergent Breeding Behavior.
J Proteome Res
January 2025
Department of Chemistry and the Beckman Institute for Advanced Science and Technology, University of Illinois Urbana─Champaign, Urbana, Illinois 61801, United States.
Variation in parenting behavior is widespread across the animal kingdom, both within and between species. There are two ecotypes of the three-spined stickleback fish () that exhibit dramatic differences in their paternal behavior. Males of the common ecotype are highly attentive fathers, tending to young from eggs to fry, while males of the white ecotype desert offspring as eggs.
View Article and Find Full Text PDFComparison of oxytocin use between singleton and twin pregnancies during induction of labor: A multicenter case-control study.
Eur J Obstet Gynecol Reprod Biol
January 2025
Hôpital Femme Mère Enfant (Hospices Civils de Lyon), Bron, France; INSERM UMR1153, Epope, France. Electronic address:
Objective: To compare the oxytocin doses used during induction, relative to the number of labor hours, between singleton and twin pregnancies.
Materials And Methods: We conducted a retrospective case-control study in two tertiary referral centers in France. Women with twin pregnancies who underwent labor induction with oxytocin in each center were eligible.
Targeted deletion of the pancreatic β-cell oxytocin receptor and its effects on metabolic regulation and β-cell health.
Front Endocrinol (Lausanne)
January 2025
Department of Psychology, University of Miami, Coral Gables, FL, United States.
The neuropeptide oxytocin (OXT) and its receptor (OXTR) have been shown to play an important role in glucose metabolism, and pancreatic islets express this ligand and receptor. In the current study, OXTR expression was identified in α-, β-, and δ-cells of the pancreatic islet by RNA hybridization, and OXT protein expression was observed only in β-cells. In order to examine the contribution of islet OXT/OXTR in glycemic control and islet β-cell heath, we developed a β-cell specific OXTR knock-out (β-KO) mouse.
View Article and Find Full Text PDFOxytocin versus carbetocin at elective Cesarean delivery in parturients with class III obesity: a double-blind randomized controlled noninferiority trial.
Can J Anaesth
January 2025
Department of Anesthesia and Pain Management, Mount Sinai Hospital, Mount Sinai Toronto, ON, Canada.
Purpose: Class III obesity (body mass index [BMI] ≥ 40 kg·m) is associated with high rates of Cesarean deliveries and postpartum hemorrhage, with increased maternal and fetal morbidity. The doses of oxytocin and carbetocin are two to four times higher at Cesarean delivery in patients with class III obesity. We sought to investigate the efficacy of carbetocin 80 µg iv compared with oxytocin 1 IU iv (plus infusion) at elective Cesarean delivery in parturients with class III obesity.
View Article and Find Full Text PDFHormonal disorders in autism spectrum disorders.
Horm Mol Biol Clin Investig
January 2025
Department of Biochemistry, Faculty of Medicine, 37555 Urmia University of Medical Sciences, Urmia, Iran.
Article Synopsis
- Autism spectrum disorder (ASD) is a complex neurobehavioral condition influenced by various genetic and environmental factors, leading to disruptions in behavior and emotions.
- A review of existing studies utilized databases like Google Scholar and PubMed to investigate the role of neural, anatomical, and chemical factors in ASD development, focusing particularly on hormones such as melatonin, serotonin, and IGF-1.
- The review aims to explore the association between these hormones and ASD, evaluating their potential as therapeutic solutions to alleviate ASD symptoms.
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