The tale of capturing Norrin.

Elife

Department of Cell Biology and Human Anatomy, University of California, Davis, Davis, United States.

Published: May 2024

AI Article Synopsis

  • Research on binding experiments sheds light on the Norrin/Wnt signaling pathway.* -
  • This pathway plays a crucial role in regulating blood vessel formation (vascularization) in the retina.* -
  • The findings could have implications for understanding eye diseases related to vascular issues.*

Article Abstract

Detailed binding experiments reveal new insights into the Norrin/Wnt signaling pathway that helps to control vascularization in the retina.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11139474PMC
http://dx.doi.org/10.7554/eLife.98933DOI Listing

Publication Analysis

Top Keywords

tale capturing
4
capturing norrin
4
norrin detailed
4
detailed binding
4
binding experiments
4
experiments reveal
4
reveal insights
4
insights norrin/wnt
4
norrin/wnt signaling
4
signaling pathway
4

Similar Publications

Rapa Nui (also known as Easter Island) is one of the most isolated inhabited places in the world. It has captured the imagination of many owing to its archaeological record, which includes iconic megalithic statues called moai. Two prominent contentions have arisen from the extensive study of Rapa Nui.

View Article and Find Full Text PDF

Background And Hypothesis: The clinical-high-risk (CHR) approach was developed to prevent psychosis through the detection of psychosis risk. CHR services are transdiagnostic in nature, therefore the appropriate management of comorbidity is a central part of care. Differential diagnosis is particularly challenging across 3 common comorbidities, schizotypal personality disorder (SPD), autism spectrum disorder (ASD), and borderline personality disorder (BPD).

View Article and Find Full Text PDF

Unidirectional social interactions are ubiquitous in real social networks whereas undirected interactions are intensively studied. We establish a voter model in a dynamical directed network. We analytically obtain the degree distribution of the evolving network at any given time.

View Article and Find Full Text PDF

The tale of capturing Norrin.

Elife

May 2024

Department of Cell Biology and Human Anatomy, University of California, Davis, Davis, United States.

Detailed binding experiments reveal new insights into the Norrin/Wnt signaling pathway that helps to control vascularization in the retina.

View Article and Find Full Text PDF

A tale of caution: How endogenous viral elements affect virus discovery in transcriptomic data.

Virus Evol

December 2023

Cluster of Microbial Ecology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen 9747 AG, The Netherlands.

Large-scale metagenomic and -transcriptomic studies have revolutionized our understanding of viral diversity and abundance. In contrast, endogenous viral elements (EVEs), remnants of viral sequences integrated into host genomes, have received limited attention in the context of virus discovery, especially in RNA-Seq data. EVEs resemble their original viruses, a challenge that makes distinguishing between active infections and integrated remnants difficult, affecting virus classification and biases downstream analyses.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!