Detailed binding experiments reveal new insights into the Norrin/Wnt signaling pathway that helps to control vascularization in the retina.
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http://dx.doi.org/10.7554/eLife.98933 | DOI Listing |
Nature
September 2024
Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Rapa Nui (also known as Easter Island) is one of the most isolated inhabited places in the world. It has captured the imagination of many owing to its archaeological record, which includes iconic megalithic statues called moai. Two prominent contentions have arisen from the extensive study of Rapa Nui.
View Article and Find Full Text PDFSchizophr Bull Open
January 2024
Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, North Terrace, Adelaide, South Australia, Australia.
Background And Hypothesis: The clinical-high-risk (CHR) approach was developed to prevent psychosis through the detection of psychosis risk. CHR services are transdiagnostic in nature, therefore the appropriate management of comorbidity is a central part of care. Differential diagnosis is particularly challenging across 3 common comorbidities, schizotypal personality disorder (SPD), autism spectrum disorder (ASD), and borderline personality disorder (BPD).
View Article and Find Full Text PDFPhys Rev E
June 2024
School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China.
Unidirectional social interactions are ubiquitous in real social networks whereas undirected interactions are intensively studied. We establish a voter model in a dynamical directed network. We analytically obtain the degree distribution of the evolving network at any given time.
View Article and Find Full Text PDFElife
May 2024
Department of Cell Biology and Human Anatomy, University of California, Davis, Davis, United States.
Detailed binding experiments reveal new insights into the Norrin/Wnt signaling pathway that helps to control vascularization in the retina.
View Article and Find Full Text PDFVirus Evol
December 2023
Cluster of Microbial Ecology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen 9747 AG, The Netherlands.
Large-scale metagenomic and -transcriptomic studies have revolutionized our understanding of viral diversity and abundance. In contrast, endogenous viral elements (EVEs), remnants of viral sequences integrated into host genomes, have received limited attention in the context of virus discovery, especially in RNA-Seq data. EVEs resemble their original viruses, a challenge that makes distinguishing between active infections and integrated remnants difficult, affecting virus classification and biases downstream analyses.
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