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Cryogenic in-memory computing using magnetic topological insulators.
Nat Mater
January 2025
Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.
Machine learning algorithms have proven to be effective for essential quantum computation tasks such as quantum error correction and quantum control. Efficient hardware implementation of these algorithms at cryogenic temperatures is essential. Here we utilize magnetic topological insulators as memristors (termed magnetic topological memristors) and introduce a cryogenic in-memory computing scheme based on the coexistence of a chiral edge state and a topological surface state.
View Article and Find Full Text PDFIntroduction: The most frequent form of diabetes in pediatric patients is polygenic autoimmune diabetes (T1D), but single-gene variants responsible for autoimmune diabetes have also been described. Both disorders share clinical features, which can lead to monogenic forms being misdiagnosed as T1D. However, correct diagnosis is crucial for therapeutic choice, prognosis and genetic counseling.
View Article and Find Full Text PDFSpatio-temporal transformers for decoding neural movement control.
J Neural Eng
January 2025
Department of Information Engineering, Electronics and Telecommunications, University of Rome La Sapienza, Piazzale Aldo Moro 5, Rome, 00185, ITALY.
Deep learning tools applied to high-resolution neurophysiological data have significantly progressed, offering enhanced decoding, real-time processing, and readability for practical applications. However, the design of artificial neural networks to analyze neural activity in vivo remains a challenge, requiring a delicate balance between efficiency in low-data regimes and the interpretability of the results. Approach: To address this challenge, we introduce a novel specialized transformer architecture to analyze single-neuron spiking activity.
View Article and Find Full Text PDFCarbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome.
Biosci Rep
January 2025
Scotland's Rural College Animal and Veterinary Sciences Research Group, Edinburgh, United Kingdom.
Approximately one in every 800 children is born with the severe aneuploid condition of Down Syndrome, a trisomy of chromosome 21. Low blood pressure (hypotension) is a common condition associated with DS and can have a significant impact on exercise tolerance and quality of life. Little is known about the factors driving this hypotensive phenotype and therefore therapeutic interventions are limited.
View Article and Find Full Text PDFCorrection to: A novel frameshift TBX4 variant in a family with ischio-coxo-podo-patellar syndrome and variable severity.
Genes Genomics
January 2025
Medical Genetics, Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.
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