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[Clinical study of Bushen Culuan Formula in treatment of ovulatory disorder infertility caused by hyperprolactinemia]. | LitMetric

[Clinical study of Bushen Culuan Formula in treatment of ovulatory disorder infertility caused by hyperprolactinemia].

Zhongguo Zhong Yao Za Zhi

China Association of Chinese Medicine Beijing 100029, China.

Published: April 2024

AI Article Synopsis

  • - This study investigates the effectiveness and safety of the Bushen Culuan Formula for treating infertility linked to high prolactin levels, specifically in patients with kidney and blood-related deficiencies.
  • - Sixty patients were split into two groups: one received the Bushen Culuan Formula along with a placebo for bromocriptine, while the other group received bromocriptine with a placebo for the formula, with various fertility metrics evaluated.
  • - Results indicated a 90% effectiveness rate in the treatment group compared to 80% in the control group, showcasing significant improvements in pregnancy rates, hormone levels, ovulation rates, and traditional Chinese medicine symptom scores for those treated with Bushen Culuan Formula.

Article Abstract

This paper aims to study the therapeutic effect and safety of Bushen Culuan Formula in the treatment of patients with infertility caused by hyperprolactinemia. Sixty patients with infertility caused by hyperprolactinemia of kidney deficiency and blood stasis were divided into the treatment group(Bushen Culuan Formula + Bromocriptine Mesylate Tablets placebo) and the control group(Bromocriptine Mesylate Tablets + Bushen Culuan Formula placebo), and ovulation rate, pregnancy rate, serum sex hormones, basal body temperature(BBT), and traditional Chinese medicine(TCM) symptom scores were observed. The results showed the clinical effective rate was 90.00% in the treatment group and 80.00% in the control group. The treatment group was able to significantly reduce the PRL level and increase the pregnancy rate, and it was superior to the control group in increasing the BBT biphasic ratio, improving the TCM symptom scores, and enhancing the ovulation rate. The results show that Bushen Culuan Formula is safe and reliable in treating ovulatory disorder infertility caused by hyperprolactinemia, with remarkable effects.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20240115.501DOI Listing

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