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Rethinking atherosclerotic cardiovascular disease prevention in the era of expanding therapies: could plaque stabilization reduce the need for lifelong treatments and polypharmacy?
Curr Opin Cardiol
January 2025
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Purpose Of Review: This review examines current evidence on pharmacologically induced plaque stabilization in the context of a growing range of new therapies. It explores the potential for a paradigm shift in atherosclerotic cardiovascular disease (ASCVD) prevention, where treatments may not need to be lifelong to achieve lasting benefits.
Recent Findings: Since 2015, over 14 novel therapies have been introduced, each shown to reduce ASCVD risk when added to standard care with statins and aspirin.
Rethinking Aspirin: Ditching the Daily "Pill"ar of Tradition.
JACC Cardiovasc Interv
May 2024
Division of Cardiology, Azienda Ospedaliero Universitaria Policlinico "G. Rodolico-San Marco, " University of Catania, Catania, Italy. Electronic address:
SOHO State of the Art Updates and Next Questions | Polycythemia Vera: Is It Time to Rethink Treatment?
Clin Lymphoma Myeloma Leuk
February 2023
Department of Oncology, ASST Sette Laghi, Varese, Italy; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Article Synopsis
- Polycythemia vera (PV) is a blood disease caused by a genetic change that leads to too many blood cells being made, mainly due to a mutation in the JAK2 gene.
- The main goal of treatment is to prevent blood clots since there’s no cure for the disease yet, and patients usually need blood draws to keep their red blood cell levels in check.
- Certain patients at higher risk may need additional treatments, like hydroxyurea or ruxolitinib, to help control their condition better and avoid serious complications like myelofibrosis.
Aspirin for Primary Prevention-Time to Rethink Our Approach.
JAMA Netw Open
April 2022
Department of Medicine, NYU Grossman School of Medicine, New York, New York.
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