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| http://dx.doi.org/10.36416/1806-3756/e20240121 | DOI Listing |
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European cancer mortality predictions for the year 2025 with focus on breast cancer.
Ann Oncol
February 2025
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address:
Background: We predicted the number of cancer deaths and rates for 2025 in the European Union (EU), its five most populous countries, and the UK, focusing on breast cancer.
Materials And Methods: We derived population data and death certificates for all cancers and major sites for the EU, France, Germany, Italy, Poland, Spain, and the UK since 1970, from the World Health Organization and United Nations databases. Estimates for 2025 were computed by linear regression on recent trends identified through Poisson joinpoint regression, considering the slope of the most recent trend segment.
Fruit, vegetables and discretionary food intake in Australian adults: Past trends and predicted progress towards population preventive health targets for 2030.
Aust N Z J Public Health
February 2025
Commonwealth Scientific and Industrial Research Organisation (CSIRO) Health & Biosecurity, Adelaide, South Australia 5000, Australia. Electronic address:
Objective: In Australia, 'improving access to and the consumption of a healthy diet' is a focus in the National Preventive Health Strategy. The objective of this paper is to describe the past trends and future projections of population intakes against the Strategy's targets of increasing fruit consumption to 2 servings per day; increasing vegetables to 5 servings; and reducing discretionary foods to <20% of total energy by 2030.
Methods: Self-reported intake data were available from an online survey of 275,170 Australian adults collected between 2015 and 2023.
The IL-6 axis in vascular inflammation: effects of IL-6 receptor blockade on vascular lesions from patients with giant-cell arteritis.
Ann Rheum Dis
March 2025
Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic (member of European Reference Network [ERN]-for rare diseases RITA), University of Barcelona, Centre de Recerca biomèdica (CRB)-CELLEX, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:
Objectives: Blocking interleukin (IL)-6-receptor with tocilizumab has been a major advance in the treatment of giant-cell arteritis (GCA), supporting a crucial role of IL-6 receptor signalling. However, nearly half of the patients are not able to maintain glucocorticoid- free remission with tocilizumab. The impact of tocilizumab on vascular lesions of GCA is largely unknown since conflicting results have been obtained by imaging.
View Article and Find Full Text PDFHidden aging: the secret role of root senescence.
Trends Plant Sci
March 2025
Molecular Plant Nutrition, Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany. Electronic address:
Root age-dependent processes have remained poorly understood. Here, we define root age-related terms in their eco-/physiological context, provide a synthesis of read-outs and traits characterizing root senescence in different root types, and follow their modulation in the light of metabolic, hormonal, and genetic control. Evidence for an endogenously regulated senescence program in roots includes changes in root anatomy, metabolism, and color, decrease in root activity, increasing levels of stress-related hormones, and increasing expression of certain transcription factors (TFs) or genes involved in oxidative stress defense.
View Article and Find Full Text PDFImpact of reimbursement reform on Finnish occupational health service trends in 2018-2022: an interrupted time series analysis.
BMJ Open
March 2025
Faculty of Medicine and Health Technology, Tampere University, Tampere, Pirkanmaa, Finland.
Objectives: In Finland, the reimbursement system for occupational health services (OHSs) was reformed on 1 January 2020 to shift the focus from curative care to preventive OHS and promote employees' work ability. We investigated the OHS trends and how the reimbursement affected them.
Design: A register-based study that used moving averages to visualise OHS trends in 2018-2022.
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