AI Article Synopsis
- Nonagenarians are expected to make up 10% of the U.S. population by 2050, but their outcomes related to nonvariceal upper gastrointestinal bleeding (NVUGIB) have not been studied before.
- The study utilized data from the National Inpatient Sample database from 2016 to 2020 and found that nonagenarians had a higher in-hospital mortality rate (4%) compared to octogenarians (3%), with lower rates of esophagogastroduodenoscopy (EGD) and blood transfusions.
- The analysis indicated that nonagenarians are at a greater risk of mortality and less likely to receive EGD for NVUGIB, highlighting the need for additional research to understand these outcomes better in
Article Abstract
Background/aims: Nonagenarians will purportedly account for 10% of the United States population by 2050. However, no studies have assessed the outcomes of nonvariceal upper gastrointestinal bleeding (NVUGIB) in this age group.
Methods: The National Inpatient Sample database between 2016 and 2020 was used to compare the clinical outcomes of NVUGIB in nonagenarians and octogenarians and evaluate predictors of mortality and the use of esophagogastroduodenoscopy (EGD).
Results: Nonagenarians had higher in-hospital mortality than that of octogenarians (4% vs. 3%, p<0.001). EGD utilization (30% vs. 48%, p<0.001) and blood transfusion (27% vs. 40%, p<0.001) was significantly lower in nonagenarians. Multivariate logistic regression analysis revealed that nonagenarians with NVUGIB had higher odds of mortality (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.3-1.7) and lower odds of EGD utilization (OR, 0.86; 95% CI, 0.83-0.89) than those of octogenarians.
Conclusions: Nonagenarians admitted with NVUGIB have a higher mortality risk than that of octogenarians. EGD is used significantly in managing NVUGIB among nonagenarians; however, its utilization is comparatively lower than in octogenarians. More studies are needed to assess predictors of poor outcomes and the indications of EGD in this growing population.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133988 | PMC |
| http://dx.doi.org/10.5946/ce.2023.130 | DOI Listing |
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