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http://dx.doi.org/10.3348/kjr.2024.0239 | DOI Listing |
J Bone Miner Res
December 2024
Division of Endocrinology/Metabolic Bone Disease Service, Hospital for Special Surgery, New York, NY.
Opportunistic screening is essential to improve the identification of individuals with osteoporosis. Our group has utilized image texture features to assess bone quality using clinical MRIs. We have previously demonstrated that greater heterogeneity of MRI texture related to history of fragility fractures, lower bone density, and worse microarchitecture.
View Article and Find Full Text PDFArch Osteoporos
December 2024
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Unlabelled: This study examines how power training affects estimated bone strength, revealing that females benefit more than males, especially in the upper limbs (radius). These findings highlight the importance of designing sex-specific exercise programs to enhance bone health. Further research is needed to optimize training duration and address site-specific differences.
View Article and Find Full Text PDFUltrasound Q
March 2025
Department of Radiology, University of Kentucky College of Medicine, Lexington, KY.
Effective presentations are crucial for disseminating knowledge and cultivating skilled learners. Cognitive load theory (CLT) offers a framework for optimizing instructional design by managing the mental effort required for learning. This article explores principles from CLT with practical suggestions to create brain-friendly presentations, focusing on intrinsic, extraneous, and germane cognitive loads.
View Article and Find Full Text PDFNanotoxicology
December 2024
Deartment of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
The cellular components of the tumor microenvironment (TME) comprise cancer cells and nonmalignant cells including stromal and immune cells. Exosomes are extracellular vesicles secreted by various types of cells that play a crucial role in intercellular communications within TME. The main goal of this study was to elucidate how exosomes of macrophage cells treated with doxorubicin (DOX) and DOX-loaded cyclodextrin-based nanosponges (DOX-CDNSs), affect melanoma cancer cell proliferation.
View Article and Find Full Text PDFAdv Mater
December 2024
Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China.
The precise manipulation of PANoptosis, a newly defined cell death pathway encompassing pyroptosis, apoptosis, and necroptosis, is highly desired to achieve safer cancer immunotherapy with tumor-specific inflammatory responses and minimal side effects. Nonetheless, this objective remains a formidable challenge. Herein, an "AND" logic-gated strategy for accurately localized PANoptosis activation, utilizing composite 3D-printed bioactive glasses scaffolds integrated with epigenetic regulator-loaded porous piezoelectric SrTiO nanoparticles is proposed.
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