AI Article Synopsis
- The study explored the antimicrobial properties of ethanol extracts from the leaves, stems, and roots of Cnidoscolus urens against multiresistant bacteria.
- Results showed that all extracts had Minimum Inhibitory Concentration (MIC) values greater than 1024 µg/mL, indicating low antimicrobial effectiveness by themselves.
- The leaf extract demonstrated significant ability to reduce MIC values for certain bacteria when combined with gentamicin and erythromycin, suggesting it may help combat antibiotic resistance.
Article Abstract
The present study aimed to evaluate the antimicrobial and modulating activity of the ethanol extract obtained from the leaves, stems, and roots of Cnidoscolus urens in multiresistant bacteria. The Minimum Inhibitory Concentration (MIC) values obtained for the extracts of leaves, stems, and roots were greater than 1024 µg/mL for all isolates. In the antimicrobial resistance modulation test, the extract of the leaves of C. urens showed a better modulating effect than that of the stems and roots for gentamicin, highlighting the reduction of MIC for Escherichia coli, Lactococcus garvieae and Staphylococcus sciuri. For erythromycin, a reduction of MIC was observed in L. garvieae, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus agalactiae. The extract from the leaves of C. urens has an important modulating effect on resistance in multiresistant bacteria, especially with gentamicin and erythromycin.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405546 | PMC |
| http://dx.doi.org/10.1007/s42770-024-01398-8 | DOI Listing |
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