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Different peripheral nerve blocks for patients undergoing total knee arthroplasty: a network meta-analysis of randomized controlled trials.

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Department of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.

Introduction: To comprehensively compare the effect of different peripheral nerve blocks for patients undergoing total knee arthroplasty (TKA).

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Department of Radiology, Section of Interventional Radiology, University of Chicago, Chicago, Illinois.

Osteoarthritis (OA) of the knee is a degenerative condition impacting numerous individuals globally. Genicular artery embolization (GAE) has emerged as an effective minimally invasive therapy for managing medically refractory OA-related pain in patients who are not eligible for surgery. This intervention works by disrupting the inflammatory and neoangiogenic pathways that contribute to pain.

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Knee osteoarthritis (OA) affects millions worldwide, leading to pain and reduced quality of life. Conventional treatments often fail to provide adequate relief, necessitating new therapeutic approaches. This study evaluated the efficacy and safety of genicular artery embolization (GAE) using permanent microspheres in patients with mild-to-moderate knee OA.

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Study Objective: A Bayesian network meta-analysis was performed to compare the analgesic efficacy of the following nerve block techniques: femoral nerve block (FNB), adductor canal block (ACB), infiltration between the popliteal artery and the capsule of the posterior knee (iPACK), and genicular nerve block (GNB) following total knee arthroplasty (TKA).

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