Synthesis of Nitrones and Nitroalkanes via Chiral Cyclic Imines.

Org Lett

College of Chemistry and Material Science, Sichuan Normal University, Chengdu, Sichuan 610066, China.

Published: June 2024

A series of structurally chiral cyclic imines efficiently yields chiral nitrones and nitroalkanes. This is the first report of the synthesis of nitro groups by C═N bond cleavage of imines through a nitrone intermediate.

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Source
http://dx.doi.org/10.1021/acs.orglett.4c01221DOI Listing

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