Currently, in the field of biomedical named entity recognition, CharCNN (Character-level Convolutional Neural Networks) or CharRNN (Character-level Recurrent Neural Network) is typically used independently to extract character features. However, this approach does not consider the complementary capabilities between them and only concatenates word features, ignoring the feature information during the process of word integration. Based on this, this paper proposes a method of multi-cross attention feature fusion. First, DistilBioBERT and CharCNN and CharLSTM are used to perform cross-attention word-char (word features and character features) fusion separately. Then, the two feature vectors obtained from cross-attention fusion are fused again through cross-attention to obtain the final feature vector. Subsequently, a BiLSTM is introduced with a multi-head attention mechanism to enhance the model's ability to focus on key information features and further improve model performance. Finally, the output layer is used to output the final result. Experimental results show that the proposed model achieves the best F1 values of 90.76%, 89.79%, 94.98%, 80.27% and 88.84% on NCBI-Disease, BC5CDR-Disease, BC5CDR-Chem, JNLPBA and BC2GM biomedical datasets respectively. This indicates that our model can capture richer semantic features and improve the ability to recognize entities.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132514PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0304329PLOS

Publication Analysis

Top Keywords

biomedical named
8
named entity
8
entity recognition
8
multi-cross attention
8
attention feature
8
feature fusion
8
character features
8
word features
8
features improve
8
features
6

Similar Publications

Molecular beacon (MB) probes have been extensively used for nucleic acid analysis. However, MB probes fail to hybridize with folded DNA or RNA. Here, we demonstrate that MB probes equipped with extra sequences complementary to the analyte, named 'tail', can increase the signal-to-background ratio by ∼40-fold and hybridization rates by ∼800-fold compared to conventional MB probes.

View Article and Find Full Text PDF

Therapeutic decision-making for older patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer highlights the importance of a comprehensive geriatric assessment (CGA). This assessment considers the functional status, comorbidities, and relevant conditions of the patient, and allows for an estimation of life expectancy, but it does not facilitate individualized treatment plans. There are also other challenges to consider related to the cardiac toxicity of the treatments and the under-representation of older patients in clinical trials.

View Article and Find Full Text PDF

Triple-action cancer therapy using laser-activated NO-releasing metallomicellar nanophotosensitizer for pyroptosis-driven immune reprogramming.

J Control Release

January 2025

Department of Biomedical Sciences and BioMedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Gwangju 61469, Republic of Korea; DR Cure Inc., Hwasun 58128, Republic of Korea. Electronic address:

Cancer photoimmunotherapy represents an intelligent and highly efficient therapeutic approach that harnesses the photothermal effect to precisely target and ablate tumor tissues, while simultaneously modulating the immune system to achieve tumor elimination. The integration of multifunctional therapeutic modalities for combined photoimmunotherapy requires advanced drug delivery systems. However, the design of a single nanoagent capable of serving as a multifunctional nanophotosensitizer remains a significant challenge.

View Article and Find Full Text PDF

Background: Although cognitive decline is a trait related to aging, some individuals are resilient to the aging process, defined as SuperAgers. Studying the neural underpinnings of SuperAgers may improve the understanding of AD pathology. In this study, our aim was to analyze amyloid and neurodegeneration imaging biomarkers in SuperAgers.

View Article and Find Full Text PDF

Demand for user authentication in virtual reality (VR) applications is increasing such as in-app payments, password manager, and access to private data. Traditionally, hand controllers have been widely used for the user authentication in VR environment, with which the users can typewrite a password or draw a pre-registered pattern; however, the conventional approaches are generally inconvenient and time-consuming. In this study, we proposed a new user authentication method based on eye-writing patterns identified using electrooculogram (EOG) recorded from four locations around the eyes in contact with the face-pad of a VR headset.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!