Solitary necrotic nodules in the liver present a diagnostic challenge due to their rarity and resemblance to metastatic tumors. We report a case where imaging revealed multiple hepatic lesions suggestive of malignancy, prompting a needle biopsy. Histopathology confirmed necrosis without malignancy. Despite advancements in imaging modalities, distinguishing solitary necrotic nodules from metastases remains difficult. Recognition of characteristic imaging features and consideration of biopsy are crucial for accurate diagnosis and management. This case underscores the importance of thorough evaluation and differential diagnosis in liver lesions to prevent unnecessary surgical interventions and ensure appropriate clinical care.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129603PMC
http://dx.doi.org/10.7759/cureus.59154DOI Listing

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