The threat landscape of biological hazards with the evolution of AI presents challenges. While AI promises innovative solutions, concerns arise about its misuse in the creation of biological weapons. The convergence of AI and genetic editing raises questions about biosecurity, potentially accelerating the development of dangerous pathogens. The mapping conducted highlights the critical intersection between AI and biological threats, underscoring emerging risks in the criminal manipulation of pathogens. Technological advancement in biology requires preventative and regulatory measures. Expert recommendations emphasize the need for solid regulations and responsibility of creators, demanding a proactive, ethical approach and governance to ensure global safety.
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http://dx.doi.org/10.3389/frai.2024.1382356 | DOI Listing |
Trends Plant Sci
December 2024
State Key Laboratory of Plant Diversity and Specialty Crops, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, Yunnan, 666303, China. Electronic address:
Micro/nanoplastics (MNPs) contamination is a potential threat to global biodiversity and ecosystem functions, with unclear ecological impacts on aboveground (AG) and belowground (BG) food webs in terrestrial ecosystems. Here, we discuss the uptake, ingestion, bioaccumulation, and ecotoxicological effects of MNPs in plants and associated AG-BG biota at various trophic levels. We propose key pathways for MNPs transfer between the AG-BG food webs and elaborate their impact on terrestrial ecosystem multifunctionality.
View Article and Find Full Text PDFFish Shellfish Immunol
December 2024
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Laboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Marine Biotechnology of Zhejiang Province, Ningbo University, Ningbo 315211, China. Electronic address:
CyHV-2 is the pathogen of herpesvirus haematopoietic necrosis (HVHN), resulting in significant economic losses in crucian carp. Although multiple oral vaccines have been developed to prevent CyHV-2, they have not achieved ideal protective effects. To improve the protective effect of oral vaccine, a combination vaccine was conducted by mixing recombinant Saccharomyces cerevisiae displaying ORF132 or ORF25 on the cell surface in a 1:1 ratio.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Biology and Biological Engineering, South China University of Technology, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, PR China. Electronic address:
Vibrio-induced diseases pose a significant threat to shrimp aquaculture. While the mechanisms underlying Vibrio penetration of shrimp shells and the gastrointestinal tract remain unclear, this study implicates chitinases as critical virulence factors. Despite their inability to utilize chitin or shrimp shells as sole carbon and nitrogen sources, three major shrimp pathogens-V.
View Article and Find Full Text PDFVirology
December 2024
Key Laboratory of Veterinary Biological Products, College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou, 450046, China. Electronic address:
Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes reproductive failure and respiratory distress and is a serious threat to the swine industry, given its continuous and rapid emergence. The knowledge of viral-host interaction could facilitate anti-PRRSV drug development. HnRNP A1 is an abundantly expressed protein which associates with RNA metabolic processes and plays multifarious roles during the reproduction cycle of multiple viruses.
View Article and Find Full Text PDFPest Manag Sci
December 2024
School of Pharmacy, Lanzhou University, Lanzhou, China.
Background: Plant diseases caused by plant pathogens pose a great threat to biodiversity and food security, and the problem of drug resistance caused by traditional antibiotics and fungicides is becoming more and more serious. It is urgent to develop new antibacterial molecules with low toxicity and high efficiency. Marinoquinoline A is an alkaloid isolated from marine actinomycetes and has a variety of pharmacological activities.
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