AI Article Synopsis
- A 41-year-old man has had a right flank swelling for 2 years, which increased in size over the last 6 months; medical examinations showed it was large, soft, and connected to muscle.
- A CT scan indicated a complex swelling, and a core biopsy initially suggested undifferentiated sarcoma, later revised to a lymphomatous malignancy after immuohistochemical tests.
- Ultimately, gene sequencing confirmed a plasmacytic infiltrate of unclear significance, leaving treatment options undecided between surgery and non-surgical methods like chemotherapy or radiation.
Article Abstract
A 41-year-old male presented with a swelling in the right flank present since 2 years. Initially, it was small in size but increased in size for the past 6 months. Examination revealed a large swelling in the right flank that was soft in consistency and attached to the deeper muscle. CT scan revealed a heterogenous complex swelling with attachment to the underlying muscle. Core biopsy of the lesion was reported as undifferentiated sarcoma. After immunohistochemistry markers, the diagnosis was revised to a malignancy of a lymphomatous origin. Gene sequencing studies and extensive higher marker studies were done and a final diagnosis of plasmacytic infiltrate of uncertain clinical significance was reported. With no further diagnostic options available, the case still remains to be a diagnostic challenge as the choice of treatment between surgical resection and nonsurgical treatment with chemotherapy and/or radiation cannot be decided upon.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126338 | PMC |
| http://dx.doi.org/10.1093/jscr/rjae300 | DOI Listing |
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