AI Article Synopsis
- The article discusses a rare case of a 69-year-old man who experienced a transition from hypothyroidism due to Hashimoto's thyroiditis to hyperthyroidism from Graves' disease after three years of L-thyroxine treatment.
- It explores potential mechanisms for this switch, indicating that the coexistence of both thyroid conditions can influence hormone levels, depending on the antibodies involved and the remaining thyroid function.
- The authors call for more research to understand these transitions and suggest monitoring patients with ongoing hyperthyroidism, even after stopping L-thyroxine therapy, for the possibility of developing Graves' disease.
Article Abstract
Our article examines a rare case where hypothyroidism due to Hashimoto's thyroiditis progressed, after a long period (three years) of L-thyroxine substitution, into confirmed hyperthyroidism due to Graves' disease in a 69-year-old man. The article explores possible mechanisms of this unusual transition based on our case and others reported in the literature. Findings suggest that the coexistence of Hashimoto's thyroiditis and Graves' disease can lead to transitions between hypothyroidism and hyperthyroidism, influenced by the predominance of involved antibodies and residual capacity of thyroid tissue. The authors emphasize the importance of further studies to better understand these transitions and identify at-risk patients. In conclusion, the article highlights the necessity of considering the rare possibility of transition to Graves' disease in patients presenting with persistent hyperthyroidism despite cessation of L-thyroxine.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11128183 | PMC |
| http://dx.doi.org/10.7759/cureus.59059 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!