We present a case of a single left hemisphere temporal-parietal stroke with subacute global aphasia and severe verbal apraxia and moderate dysphagia. The patient underwent a combined transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) and language stimulation with Virtual Reality Rehabilitation System (VRRS). Patient was treated in a 1-h session, for 5 days a week, for 4 consecutive weeks. After treatment, evident improvements in the comprehension of oral and written language, swallowing abilities, and caregiver burden were detected. Power spectrum analysis of EEG data revealed significant enhancements of , , and waves from baseline to follow-up. These preliminary results seem to confirm the reliability of the tDCS translational application in conjunction with computer-based cognitive treatment for language disorders in a patient with stroke-induced aphasia.
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http://dx.doi.org/10.1002/ccr3.8928 | DOI Listing |
Biomedicine (Taipei)
December 2024
School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.
Introduction: Our previous research demonstrated that a large language model (LLM) based on the transformer architecture, specifically the MegaMolBART encoder with an XGBoost classifier, effectively predicts the blood-brain barrier (BBB) permeability of compounds. However, the permeability coefficients of compounds that can traverse this barrier remain unclear. Additionally, the absorption, distribution, metabolism, and excretion (ADME) characteristics of substances obtained from the Natural Product Research Laboratory (NPRL) at China Medical University Hospital (CMUH) have not yet been determined.
View Article and Find Full Text PDFEgypt Heart J
January 2025
Department of Emergency Medicine, Ümraniye Education and Research Hospital, University of Health Sciences, Site Mahallesi, Adıvar Sokak, No 44/15, Ümraniye, İstanbul, Turkey.
Background: Heart failure is a critical cardiovascular condition, necessitating comprehensive treatment approaches and contributing to elevated mortality rates. This study aimed to evaluate the effect of the prognostic nutritional index (PNI) on the prognosis of geriatric patients diagnosed with acute heart failure.
Results: A total of 104 patients were included and evaluated retrospectively in this study; 57.
Sensors (Basel)
November 2024
Remote Sensing Lab, Department of Astronomy, Astrophysics and Space Engineering, Indian Institute of Technology, Indore 453552, India.
Forests play a critical role in the global carbon cycle, with carbon storage being an important carbon pool in the terrestrial ecosystem with tree crown size serving as a versatile ecological indicator influencing factors such as tree growth, wind resistance, shading, and carbon sequestration. They help with habitat function, herbicide application, temperature regulation, etc. Understanding the relationship between tree crown area and stock volume is crucial, as it provides a key metric for assessing the impact of land-use changes on ecological processes.
View Article and Find Full Text PDFJ Med Internet Res
December 2024
Center for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.
Background: In the United States, racial and ethnic disparities in substance use treatment outcomes are persistent, especially among underrepresented minority (URM) populations. Technology-based interventions (TBIs) for substance use treatment show promise in reducing barriers to evidence-based treatment, yet no studies have described how TBIs may impact racial or ethnic health equity.
Objective: This study explored whether TBIs in substance use treatment research promote health equity among people who identify as African American or Black, Hispanic or Latino, and American Indian or Alaska Native through their inclusion in research.
JMIR Serious Games
December 2024
Department of Otorhinolaryngology Hörzentrum, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine-University, Düsseldorf, Germany.
Background: Cochlear implants are implanted hearing devices; instead of amplifying sounds like common hearing aids, this technology delivers preprocessed sound information directly to the hearing (ie, auditory) nerves. After surgery and the first cochlear implant activation, patients must practice interpreting the new auditory sensations, especially for language comprehension. This rehabilitation process is accompanied by hearing therapy through face-to-face training with a therapist, self-directed training, and computer-based auditory training.
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