AI Article Synopsis
- This study investigates antimicrobial resistance patterns and the prevalence of hospital-acquired infections (HAIs), specifically focusing on common bacteria involved and the challenges posed by drug-resistant strains.
- Conducted over six months at Imam Khomeini Hospital in Ilam, Iran, the analysis included 123 patients and identified significant levels of multidrug-resistant isolates, particularly methicillin-resistant Staphylococcus aureus (MRSA).
- Results indicated that respiratory infections were the most common type of HAI, especially in older patients, underlining the need for better antibiotic use and infection control to combat these healthcare issues.
Article Abstract
Objective: This research study was undertaken to investigate antimicrobial resistance patterns and the prevalence of hospital-acquired infections (HAIs). The study focuses on common microorganisms responsible for HAIs and explores emerging challenges posed by antimicrobial drug-resistant isolates.
Methods: A comprehensive analysis of 123 patients with HAIs, hospitalized in surgical department and intensive care unit (ICU) at Imam Khomeini Hospital, Ilam, Iran, was conducted over a six-month period. Pathogenic bacterial isolates, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Staphylococcus aureus (VRSA), were isolated and subjected to antibiotic susceptibility testing.
Results: The study findings revealed a significant prevalence of multidrug-resistant (MDR) isolates, of which 73.3% were MRSA. Notably, 6.7% of S. aureus isolates exhibited resistance to vancomycin, indicating the emergence of VRSA. Respiratory infections were identified as the most prevalent HAI, constituting 34.67% of cases, often arising from extended ICU stays and invasive surgical procedures. Furthermore, patients aged 60 and above, particularly those associated with MDR, exhibited higher vulnerability to HAI.
Conclusions: This research sheds light on the intricate interplay between drug resistance and HAI, highlighting the imperative role of rational antibiotic use and infection control in addressing this critical healthcare challenge.
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| http://dx.doi.org/10.1007/s11033-024-09580-9 | DOI Listing |
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