The Role of Genetics on Psoriasis Susceptibility, Comorbidities, and Treatment Response.

Dermatol Clin

Department of Dermatology, University of California San Francisco, 2340 Sutter Street, Box 0808, N431, San Francisco, CA 95115, USA. Electronic address:

Published: July 2024

AI Article Synopsis

  • The review discusses recent progress in understanding the genetics of psoriasis through various research methods, such as genome-wide association studies and exome-sequencing.
  • It covers how different genetic variants can influence not only psoriasis itself but also related health conditions (comorbidities).
  • The review also highlights the relationship between genetic variations and how patients respond to different treatments for psoriasis.

Article Abstract

This review highlights advances made in psoriasis genetics, including findings from genome-wide association studies, exome-sequencing studies, and copy number variant studies. The impact of genetic variants on various comorbidities and therapeutic responses is discussed.

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Source
http://dx.doi.org/10.1016/j.det.2024.02.005DOI Listing

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