Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives.

Molecules

Medicinal Chemistry and Molecular and Cellular Oncogenesis (MCO) Program, The Wistar Institute, Philadelphia, PA 19104, USA.

Published: May 2024

AI Article Synopsis

  • - Quinazolines are a key group of heterocyclic compounds with important uses in organic synthesis and medicinal chemistry due to their diverse biological and pharmacological properties.
  • - A variety of synthetic methods have been developed to create quinazolines and their derivatives.
  • - The review article discusses recent synthetic techniques for producing compounds featuring the quinazoline structure, specifically through transition metal-catalyzed reactions.

Article Abstract

Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11124210PMC
http://dx.doi.org/10.3390/molecules29102353DOI Listing

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