Plasma applications in biomedicine represent a groundbreaking intersection between physics and life sciences, unveiling novel approaches to disease treatment and tissue regeneration [...].
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http://dx.doi.org/10.3390/biomedicines12051029 | DOI Listing |
Neuropsychiatr Dis Treat
December 2024
Department of Neurology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People's Republic of China.
Parkinson's disease (PD) is primarily recognized for its motor symptoms, yet non-motor symptoms (NMS) such as neuropsychiatric disturbances, sleep disorders, autonomic dysfunction, and sensory abnormalities significantly contribute to the disease's overall burden. While traditional pharmacological and surgical treatments have primarily targeted motor symptoms, alternative therapies such as acupuncture, cognitive therapy, and Traditional Chinese Medicine (TCM) are gaining attention for managing NMS. This review provides a comprehensive analysis of alternative therapies for NMS in PD, drawing on evidence from international guidelines and TCM.
View Article and Find Full Text PDFCold atmospheric pressure plasma (CAPP) comprises an ensemble of ionized gas, neutral particles, and/or reactive species. Electricity is frequently used to produce CAPP via a variety of techniques, including plasma jets, corona discharges, dielectric barrier discharges, and glow discharges. The type and flow rates of the carrier gas(es), temperature, pressure, and vacuum can all be altered to control the desired properties of the CAPP.
View Article and Find Full Text PDFBiopharm Drug Dispos
December 2024
Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, China.
Amphotericin B (AmB) has been a cornerstone in the treatment of invasive fungal infections for over 6 decades. Compared with conventional amphotericin B deoxycholate (AmB-DOC), liposomal amphotericin B has comparable efficacy but less nephrotoxicity. The main purpose of this study was to investigate the reason why liposomal amphotericin B has similar therapeutic effects but lower toxicity and the differences of distribution in humans between liposomal amphotericin B and AmB-DOC.
View Article and Find Full Text PDFAnal Chem
December 2024
Department of Chemistry, National Chung Hsing University, Taichung City 402202, Taiwan, ROC.
Four-dimensional printing (4DP) technologies can expand the functionality of stimuli-responsive devices to enable the integration of multiple stimuli-responsive parts into a compact device. Herein, we used digital light processing three-dimensional printing technique, flexible photocurable resins, and photocurable resins of the temperature-responsive hydrogels comprising -isopropylacrylamide (NIPAM), ,'-methylenebis(acrylamide) (MBA), and graphene for 4DP of a lab-on-valve (LOV) solid-phase extraction (SPE) device. This device featured flow manifolds and a monolithic packing connected by four near-infrared (NIR)-actuated temperature-responsive switching valves composed of a poly(NIPAM/MBA) (PNM) ball pushing a flexible membrane.
View Article and Find Full Text PDFAdv Healthc Mater
December 2024
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, USA.
Both rigid plastics and soft hydrogels find ample applications in engineering and medicine but bear their own disadvantages that limit their broader applications. Bonding these mechanically dissimilar materials may resolve these limitations, preserve their advantages, and offer new opportunities as biointerfaces. Here, a robust adhesion strategy is proposed to integrate highly entangled tough hydrogels and diverse plastics with high interfacial adhesion energy and strength.
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