Turmeric ( L.) is a perennial tuberous plant from the genus (Zingiberaceae) and has been widely used in foods for thousands of years. The present study examined the ethanol extract of turmeric for its chemical composition, antimicrobial activity, and free radical scavenging properties. UHPLC-MS/MS analysis tentatively identified eight compounds in the turmeric extract. Potential antimicrobial effects of 0.1, 1.0, and 10 mg turmeric equivalents (TE)/mL were evaluated in vitro against a variety of Gram-negative bacteria (i.e., , , and sp.) and Gram-positive bacteria (i.e., , , and ). Concentrations of 0.1 and 1.0 mg TE/mL inhibited the growth of and significantly suppressed that of sp., , and . The growth of all strains, including , was inhibited by 10 mg TE/mL. Moreover, free radical scavenging capacities were determined using HO, ABTS, and DPPH (HOSC, ABTS, and RDSC, respectively) radicals. The turmeric ethanol extract had a TPC value of 27.12 mg GAE/g, together with HOSC, RDSC, and ABTS values of 1524.59, 56.38, and 1.70 μmol TE/g, respectively. Our results suggest that turmeric extract has potential applications for use in functional foods to reduce microbial burdens and oxidative stress-related health problems.
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http://dx.doi.org/10.3390/foods13101550 | DOI Listing |
Inflammopharmacology
December 2024
Department of Pharmacology, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Punjab, Pakistan.
Juice and decoction of leaves of Suaeda fruticosa, a halophytic medicinal plant of Cholistan desert, is traditionally used to treat rheumatism. The current study was carried out to probe into in vivo anti-nociceptive, anti-inflammatory, and anti-arthritic potential of ethanolic extract of the whole plant of S. fruticosa (Et-SF) and its bioactive molecules.
View Article and Find Full Text PDFNat Prod Res
December 2024
Department of Zoology, GC University, Lahore, Pakistan.
Inhibiting angiogenesis with plant-derived bioactive compounds can inhibit tumour progression. Antiangiogenic potential of was analysed by preparing and analysing ethanolic extracts of by GC-MS and HPLC to identify bioactive components. In-vivo blood vessel formation assays in mice and chorioallantoic membrane assays (CAM) in eggs were employed to assess the antiangiogenic effects.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia.
Rhazya stricta, a perennial shrub native to the Middle East and South Asia, has been used in traditional medicine for various therapeutic purposes, including antimicrobial action. The current study aimed to compare the antifungal properties of 96% and 50% ethanolic extracts of R. stricta leaves and their biogenic silver nanoparticles (AgNPs).
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China. Electronic address:
Dendrobium flexicaule (DF) is an endemic plant primarily found in the mountains of central China with important medicinal and edible values. In traditional Chinese medicine, DF has the effects of nourishing stomach and "Yin", and clearing heat. At present, no studies have explored the mechanisms by which Dendrobium flexicaule polysaccharides (DFP) exert pre-protect effects against alcohol-induced gastric mucosal injury.
View Article and Find Full Text PDFAnimal
December 2024
Physiologie de la Reproduction et des Comportements, CNRS, INRAE, Université de Tours, 37380 Nouzilly, France.
Intravaginal sponges impregnated with the progesterone (P4) analogue fluorogestone acetate (FGA) induce synchronous oestrous behaviour and normal ovulatory cycle in goats. To explore alternatives using natural P4 from plants, we developed a method of ethanolic extraction and a specific enzyme immunoassay (EIA) to measure P4 in the different parts of the walnut tree Juglans regia. We found a very high concentration of P4, specifically in the leaves of the three most common French varieties (∼100 mg/kg of DM) but not in flowers, fruits, septa, husk, oil or cake.
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