Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. The standard and most effective treatment is wide resection of the tumor combined with neoadjuvant chemotherapy. Adolescent idiopathic scoliosis (AIS) is a genetically determined three-dimensional spinal deformity, which occurs in teenage patients and is mostly progressive. The basic management strategy is surgical treatment when the curve exceeds 50 degrees. However, the indications are different in oncologic patients. The aim of this study was to describe a case of adolescent scoliosis with osteosarcoma of the pelvis. The authors conducted a scoping review using PubMed and Embase to analyze the state of knowledge. The presented paper is the first report of pelvis osteosarcoma coexisting with adolescent idiopathic scoliosis. Treatment for this complex case finished with very good results, with no recurrence observed during the nine-year follow-up.
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http://dx.doi.org/10.3390/children11050607 | DOI Listing |
J Pediatr Endocrinol Metab
January 2025
School of Medicine, University of Minho, Braga, Portugal.
Objectives: Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) levels (>5 mUI/L) and normal total and free thyroxine levels (fT4). There is ongoing debate over whether mild SCH should be treated. This study aims to assess the clinical course of normoponderal pediatric patients with SCH.
View Article and Find Full Text PDFClin Biomech (Bristol)
December 2024
Hacettepe University, Faculty of Physical Therapy and Rehabilitation, Ankara, Turkey.
Background: In this study, we aimed to evaluate the viscoelastic properties of the superficial back muscles of adolescent idiopathic scoliosis patients with Lenke Type 1A and 1B curves compared to their healthy peers.
Methods: 20 participants with adolescent idiopathic scoliosis and 20 healthy peers were evaluated. Cobb angle was recorded for scoliosis participants.
Curr Rev Musculoskelet Med
December 2024
Wake Forest School of Medicine, Department of Orthopaedic Surgery, 1 Medical Center Blvd, Winston Salem, NC, 27103, USA.
Purpose Of Review: Adolescent idiopathic scoliosis (AIS) is a disabling spinal pathology, with a significant morbidity if left untreated. This review investigates the recent advances in the diagnosis and management of AIS.
Recent Findings: Low radiation techniques have become a paramount focus in the management of patient's with AIS.
Eur Spine J
December 2024
Department of Orthopaedic Surgery, Faculty of Medicine, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Purpose: To devise a mathematical model for estimating the intraoperative lowest instrumented vertebra (LIV) tilt angle using preoperative supine left side-bending (LSB) radiographs in adolescent idiopathic scoliosis (AIS) patients with Lenke type 1 and 2 (non-AR curves), and to review its clinical and radiological outcomes.
Methods: The mathematical model for the adjusted LSB LIV tilt angle (α) measured preoperatively, was expressed as the sum of preoperative LSB LIV tilt angle (x) and LIV displacement angle (y) (α = x + y). This model was validated through inter-rater and intra-rater analysis in Part I of the study.
Eur Spine J
December 2024
Foshan Clinical Medical College of Guangzhou University of Traditional Chinese Medicine, Foshan, China.
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