AI Article Synopsis

  • Thyrotoxic cardiomyopathy is a serious complication from thyrotoxicosis that can lead to acute heart failure, highlighting the need for early diagnosis and management.* -
  • A patient presented with symptoms of dyspnea and acute heart failure, leading to a diagnosis of thyrotoxic cardiomyopathy and subsequent treatment with diuretics and antiarrhythmics.* -
  • Post-treatment, the patient's heart function improved significantly, showcasing the potential for recovery and the importance of timely intervention in similar cases.*

Article Abstract

Rationale: Thyrotoxic cardiomyopathy is a rare but severe complication of thyrotoxicosis, leading to episodes of acute heart failure. This case report highlights a rare presentation of thyrotoxic cardiomyopathy with low-output heart failure, emphasizing the importance of early diagnosis and comprehensive management. The report aims to increase awareness among clinicians about the potential reversibility of this condition and the effective strategies for managing such complex cases.

Patient Concerns: This patient presented with dyspnea and chest constriction, without any antecedent predisposing factors. Subsequently, the patient abruptly manifested symptoms indicative of acute heart failure during outpatient consultation. Electrocardiography revealed rapid atrial fibrillation with type A preexcitation syndrome, whereas cardiac ultrasonography demonstrated global cardiac enlargement with a diminished ejection fraction (EF).

Diagnoses: After a comprehensive evaluation, the patient was diagnosed with thyrotoxic cardiomyopathy, acute heart failure, and atrial fibrillation with preexcitation syndrome.

Interventions: Immediate interventions comprised diuretic administration, oxygen therapy, and antiarrhythmic agents, addressing acute heart failure concomitant with preexcitation syndrome. Following a fortnight of comprehensive therapeutic measures, the patient was discharged with a prescription for oral medications, notably methimazole.

Outcomes: Following the intervention, the patient showed significant improvement with the resolution of heart failure symptoms and dyspnea, restoration of sinus rhythm, improved left ventricular ejection fraction (LVEF improved from 36% to 45%), and normalization of thyroid function. These outcomes underscore the efficacy of the intervention strategy and offer a hopeful prognosis for similar cases.

Lessons: Thyrotoxicosis may cause cardiomyopathy in patients with heart failure that manifests as dilated cardiac chambers. Clinicians should carefully screen patients for this reversible condition. Diagnosis requires a comprehensive assessment of various tests, and the therapeutic goal is to restore normal thyroid function.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11124643PMC
http://dx.doi.org/10.1097/MD.0000000000038305DOI Listing

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