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Pen direct writing of multiplex-LFIA for detection of thiamphenicol and tylosin in milk.
Mikrochim Acta
January 2025
Tyndall National Institute, University College Cork, Lee Maltings Complex, Dyke Parade, Cork, T12R5CP, Ireland.
Therapeutic and misuse of veterinary drugs, such as antibiotics, can increase the potential risk of residue contamination in animal-derived food products. For milk, these residual antibiotics can have an impact on efficiency in dairy processing factories, as well as economic loss, and can also cause side effects on consumer health. Lateral flow immunoassays (LFIAs) are gaining popularity for their ease of use, low cost and their fulfilment to the REASSURED (real-time connection/monitoring, easy sampling, affordable, specific, user-friendly, rapid/robust, equipment free, deliverable to end user) criteria.
View Article and Find Full Text PDFThe Formulation and Evaluation of Customized Prednisolone Gel Tablets Prepared by an Automated Extrusion-Based Material Deposition Method.
Pharmaceutics
November 2024
Faculty of Medicine, Institute of Pharmacy, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
: An automated extrusion-based material deposition is a contemporary and rapid method for pharmaceutical dose-dispensing and preparing (printing) individualized solid dosage forms. The aim of this study was to investigate and gain knowledge of the feasibility of automated extrusion-based material deposition technology in preparing customized prednisolone (PRD)-loaded gel tablets for veterinary applications (primarily for dogs and cats). : The PRD loads of the extrusion-based deposited gel tablets were 0.
View Article and Find Full Text PDFIdentifying influential nodes in brain networks via self-supervised graph-transformer.
Comput Biol Med
December 2024
Center for Brain and Brain-Inspired Computing Research, School of Computer Science, Northwestern Polytechnical University, Xi'an, China. Electronic address:
Background: Studying influential nodes (I-nodes) in brain networks is of great significance in the field of brain imaging. Most existing studies consider brain connectivity hubs as I-nodes such as the regions of high centrality or rich-club organization. However, this approach relies heavily on prior knowledge from graph theory, which may overlook the intrinsic characteristics of the brain network, especially when its architecture is not fully understood.
View Article and Find Full Text PDFInsights from a National Survey on Controlled Substance Diversion Practices in U.S. Hospital Pharmacies: Opportunities for Enhanced Surveillance and Compliance.
Pharmacy (Basel)
December 2024
Department of Medical Affairs, Becton Dickinson and Company, Franklin Lakes, NJ 07417, USA.
This study explored controlled substance (CS) diversion surveillance practices within hospital pharmacies across the United States. A survey with questions based on published CS diversion risk points was conducted in May 2024. A total of 66 participants from 31 states responded, with 54.
View Article and Find Full Text PDFOn-farm supplementation of rumen-protected niacin: A randomized clinical trial.
J Dairy Sci
January 2025
Department of Animal Science, Michigan State University, East Lansing, MI 48824. Electronic address:
B vitamins, including niacin (vitamin B), are synthesized by rumen microbes, but supplementation may provide additional benefits for ruminant health and productivity. Supplementing rumen-protected niacin (RPN) during the transition period can reduce lipolysis after calving and, consequently, may improve health and fertility of dairy cattle later in lactation. Our objective was to determine if supplementing RPN during the first 21 DIM would improve the health of dairy cows on a commercial dairy farm.
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