The enantioselective synthesis of pharmacologically important 14-hydroxy-6-oxomorphinans is described. 4,5-Desoxynaltrexone and 4,5-desoxynaloxone were prepared using this route and their biological activities against the opioid receptors were measured.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155717 | PMC |
| http://dx.doi.org/10.1039/d4cc01788a | DOI Listing |
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