AI Article Synopsis
- A 75-year-old woman experienced persistent hiccups during general anesthesia with remimazolam for corneal transplantation, which continued despite treatment with antipsychotic drugs.
- Hiccups ceased when remimazolam was stopped after surgery, indicating a possible link between the drug and the hiccups.
- The report suggests that higher levels of remimazolam may trigger hiccups, and anesthesiologists should consider alternative treatments if hiccups are resistant to standard interventions.
Article Abstract
Background: Previous reports have described hiccups during general anesthesia that were possibly induced by drugs, including benzodiazepines. However, there are few reports of hiccups caused by remimazolam. Case presentation A 75-year-old woman underwent corneal transplantation under general anesthesia with remimazolam. She presented with hiccups once the effects of muscle relaxants used during induction wore off, which persisted even after various treatments, such as the administration of antipsychotic drugs. However, when remimazolam administration was terminated after surgery to awaken the patient, the hiccups stopped and did not recur after extubation. Evaluation of predicted blood levels of remimazolam suggests that higher levels of remimazolam might cause hiccups.
Conclusion: Remimazolam might induce hiccups during general anesthesia. Anesthesiologists should consider administering muscle relaxants or changing the anesthetic in cases of refractory hiccups under general anesthesia.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126544 | PMC |
| http://dx.doi.org/10.1186/s40981-024-00714-3 | DOI Listing |
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