AI Article Synopsis

  • - This study is the first to investigate the effectiveness and safety of transcranial pulse stimulation (TPS) as a treatment for ADHD in young adolescents (ages 12-17) in Hong Kong.
  • - Conducted as a double-blind, randomized, sham-controlled trial with 30 ADHD-diagnosed participants, evaluations were made before and after TPS treatment as well as at 1 and 3-month follow-ups.
  • - Results showed that the TPS group had a consistent 30% reduction in ADHD symptoms, as measured by SNAP-IV scores, indicating that TPS is a promising and safe add-on treatment for managing ADHD.

Article Abstract

Background: This is the first study to evaluate the efficacy and safety of transcranial pulse stimulation (TPS) for the treatment of attention-deficit/hyperactivity disorder (ADHD) among young adolescents in Hong Kong.

Methods: This double-blind, randomized, sham-controlled trial included a TPS group and a sham TPS group, encompassing a total of 30 subjects aged 12-17 years who were diagnosed with ADHD. Baseline measurements SNAP-IV, ADHD RS-IV, CGI and executive functions (Stroop tests, Digit Span) and post-TPS evaluation were collected. Both groups were assessed at baseline, immediately after intervention, and at 1-month and 3-month follow-ups. Repeated-measures ANOVAs were used to analyze data.

Results: The TPS group exhibited a 30% reduction in the mean SNAP-IV score at postintervention that was maintained at 1- and 3-month follow-ups.

Conclusion: TPS is an effective and safe adjunct treatment for the clinical management of ADHD.

Clinical Trial Registration: ClinicalTrials.Gov, identifier NCT05422274.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112118PMC
http://dx.doi.org/10.3389/fneur.2024.1364270DOI Listing

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