AI Article Synopsis

  • - Routine immunization programs in low- and lower-middle-income countries (LMICs) have seen improvements in vaccination coverage from 2000 to 2020, which helps reduce vaccine-preventable diseases (VPDs)
  • - A study analyzed data from 174 household surveys across 41 LMICs using advanced statistical methods, revealing marked increases in vaccination rates, especially in East Africa, though many countries are projected to fall short of the 2030 coverage goals
  • - The conclusion emphasizes the need for LMICs to address ongoing urban-rural and socioeconomic gaps in vaccination access by enhancing health systems and involving communities to ensure equitable vaccine distribution

Article Abstract

Introduction: Routine immunization programs have focused on increasing vaccination coverage, which is equally important for decreasing vaccine-preventable diseases (VPDs), particularly in low- and lower-middle-income countries (LMICs). We estimated the trends and projections of age-appropriate vaccination coverage at the regional and national levels, as well as place of residence and wealth index in LMICs.

Methods: In total, 174 nationally representative household surveys from 2000 to 2020 from 41 LMICs were included in this study. Bayesian hierarchical regression models were used to estimate trends and projections of age-appropriate vaccination.

Results: The trend in coverage of age-appropriate Bacillus Calmette-Guérin (BCG), third dose of diphtheria, tetanus, and pertussis (DTP3), third dose of polio (polio3), and measles-containing vaccine (MCV) increased rapidly from 2000 to 2020 in LMICs. Findings indicate substantial increases at the regional and national levels, and by area of residence and socioeconomic status between 2000 and 2030. The largest rise was observed in East Africa, followed by South and Southeast Asia. However, out of the 41 countries, only 10 countries are estimated to achieve 90% coverage of the BCG vaccine by 2030, five of DTP3, three of polio3, and none of MCV. Additionally, by 2030, wider pro-urban and -rich inequalities are expected in several African countries.

Conclusion: Significant progress in age-appropriate vaccination coverage has been made in LMICs from 2000 to 2020. Despite this, projections show many countries will not meet the 2030 coverage goals, with persistent urban-rural and socioeconomic disparities. Therefore, LMICs must prioritize underperforming areas and reduce inequalities through stronger health systems and increased community engagement to ensure high coverage and equitable vaccine access.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11111938PMC
http://dx.doi.org/10.3389/fpubh.2024.1371258DOI Listing

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