Personalized medicine and nutrition in hepatology for preventing chronic liver disease in Mexico.

Front Nutr

Department of Genomic Medicine in Hepatology, Civil Hospital of Guadalajara, Fray Antonio Alcalde, Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.

Published: May 2024

AI Article Synopsis

  • * Advances in Genomic Medicine and Nutrition reveal variations in genetic and lifestyle risks for chronic liver disease across different countries, paving the way for Personalized Medicine and Nutrition (PerMed-Nut) approaches.
  • * Mexico's diverse ancestral background necessitates the development of a PerMed-Nut model addressing specific liver-related diseases, alongside improved training for health professionals in genomic hepatology to enhance prevention efforts.

Article Abstract

Chronic liver disease is a global health issue. Patients with chronic liver disease require a fresh approach that focuses on the genetic and environmental factors that contribute to disease initiation and progression. Emerging knowledge in the fields of Genomic Medicine and Genomic Nutrition demonstrates differences between countries in terms of genetics and lifestyle risk factors such as diet, physical activity, and mental health in chronic liver disease, which serves as the foundation for the implementation of Personalized Medicine and Nutrition (PerMed-Nut) strategies. Most of the world's populations have descended from various ethnic groupings. Mexico's population has a tripartite ancestral background, consisting of Amerindian, European, and African lineages, which is common across Latin America's regional countries. The purpose of this review is to discuss the genetic and environmental components that could be incorporated into a PerMed-Nut model for metabolic-associated liver disease, viral hepatitis B and C, and hepatocellular carcinoma in Mexico. Additionally, the implementation of the PerMed-Nut approach will require updated medicine and nutrition education curricula. Training and equipping future health professionals and researchers with new clinical and investigative abilities focused on preventing liver illnesses in the field of genomic hepatology globally is a vision that clinicians and nutritionists should be concerned about.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11113077PMC
http://dx.doi.org/10.3389/fnut.2024.1379364DOI Listing

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