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The association between multilingual experience factors and cognitive functioning in older adults: A Lifelines study.
J Gerontol B Psychol Sci Soc Sci
January 2025
Linguistics and English as a Second Language, Faculty of Arts, University of Groningen, Groningen, the Netherlands.
Objectives: The complex life experience of speaking two or more languages has been suggested to preserve cognition in older adulthood. This study aimed to investigate this further by examining the relationship between multilingual experience variables and cognitive functioning in a large cohort of older adults in the diversely multilingual north of the Netherlands.
Method: 11,332 older individuals participating in the Lifelines Cohort Study completed a language experience questionnaire.
Deferred Lateral Margin Control in the Surgical Treatment of Genital Paget's Disease and Lentiginous Vulvar Melanoma.
J Clin Med
December 2024
Department of Dermatology, University Clinic of Navarra, 28027 Madrid, Spain.
Some skin tumors can extend beyond their clinical appearance. This presents an additional challenge, especially when the affected area is the genital region, which is more difficult for both the patient and the physician to access and monitor due to its location and anatomical characteristics. The treatment of these lesions is complex, and literature postulates Mohs surgery as the best therapeutic option.
View Article and Find Full Text PDFExploring the Metabolic Impact of FLASH Radiotherapy.
Cancers (Basel)
January 2025
Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
FLASH radiotherapy (FLASH RT) is an innovative modality in cancer treatment that delivers ultrahigh dose rates (UHDRs), distinguishing it from conventional radiotherapy (CRT). FLASH RT has demonstrated the potential to enhance the therapeutic window by reducing radiation-induced damage to normal tissues while maintaining tumor control, a phenomenon termed the FLASH effect. Despite promising outcomes, the precise mechanisms underlying the FLASH effect remain elusive and are a focal point of current research.
View Article and Find Full Text PDFEnvironmental DNA Insights into the Spatial Status of Fish Diversity in the Mainstem of the Jialing River.
Animals (Basel)
January 2025
Laboratory of Water Ecological Health and Environmental Safety, School of Life Sciences, Chongqing Normal University, Chongqing 401331, China.
Preserving healthy river habitats is essential for maintaining fish diversity. Over time, anthropogenic activities have severely damaged river habitats, leading to notable changes in fish diversity patterns. Conducting thorough and reliable investigations into fish diversity is crucial for assessing anthropogenic impacts on diversity.
View Article and Find Full Text PDFImpact of Pediatric Posterior Fossa Tumor Treatments on Working Memory Tracts Using Resting-State fMRI and Tractography.
J Neuroimaging
January 2025
Toulouse NeuroImaging Center (ToNIC), INSERM, University of Toulouse Paul Sabatier, Toulouse, France.
Background And Purpose: Working memory, a primary cognitive domain, is often impaired in pediatric brain tumor survivors, affecting their attention and processing speed. This study investigated the long-term effects of treatments, including surgery, radiotherapy (RT), and chemotherapy (CT), on working memory tracts in children with posterior fossa tumors (PFTs) using resting-state functional MRI (rs-fMRI) and diffusion MRI tractography.
Methods: This study included 16 medulloblastoma (MB) survivors treated with postoperative RT and CT, 14 pilocytic astrocytoma (PA) survivors treated with surgery alone, and 16 healthy controls from the Imaging Memory after Pediatric Cancer in children, adolescents, and young adults study (NCT04324450).
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