The coronary angiogram is the gold standard for evaluating the severity of coronary artery disease stenoses. Presently, the assessment is conducted visually by cardiologists, a method that lacks standardization. This study introduces DeepCoro, a ground-breaking AI-driven pipeline that integrates advanced vessel tracking and a video-based Swin3D model that was trained and validated on a dataset comprised of 182,418 coronary angiography videos spanning 5 years. DeepCoro achieved a notable precision of 71.89% in identifying coronary artery segments and demonstrated a mean absolute error of 20.15% (95% CI: 19.88-20.40) and a classification AUROC of 0.8294 (95% CI: 0.8215-0.8373) in stenosis percentage prediction compared to traditional cardiologist assessments. When compared to two expert interventional cardiologists, DeepCoro achieved lower variability than the clinical reports (19.09%; 95% CI: 18.55-19.58 vs 21.00%; 95% CI: 20.20-21.76, respectively). In addition, DeepCoro can be fine-tuned to a different modality type. When fine-tuned on quantitative coronary angiography assessments, DeepCoro attained an even lower mean absolute error of 7.75% (95% CI: 7.37-8.07), underscoring the reduced variability inherent to this method. This study establishes DeepCoro as an innovative video-based, adaptable tool in coronary artery disease analysis, significantly enhancing the precision and reliability of stenosis assessment.
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http://dx.doi.org/10.1038/s41746-024-01134-4 | DOI Listing |
Case Rep Cardiol
December 2024
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
A 48-year-old male with a history of hyperlipidemia presented to the emergency department with chest pain. Electrocardiographic abnormalities indicated an acute coronary syndrome. Urgent coronary angiography revealed nondominant right coronary artery (RCA) occlusion.
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December 2024
The Third Affiliated Hospital of Zhejiang, Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
Cureus
November 2024
Department of Cardiology, Aizawa Hospital, Matsumoto, JPN.
This case report describes a 15-year-old boy who presented with vasospastic angina (VSA). His symptoms included chest and back pain, nausea, and respiratory distress. After undergoing diagnostic tests, including coronary angiography and an acetylcholine provocation test, the patient was diagnosed with VSA.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Cardiology Department, University Hospital Agadir, Medical School of Medicine & Pharmacy Ibn Zohr University, Agadir, Morocco.
An anomalous origin of the right coronary artery from the opposite sinus (R- ACAOS) with interarterial course is a very rare congenital anomaly with an increased risk of sudden cardiac death. A 29-year-old woman was admitted for exertional angina pectoris. A coronary computed tomography angiography with 3D multiplanar reconstruction revealed an R-ACAOS running between the aorta and pulmonary artery with high anatomical features and no ischemia-induced at the stress test.
View Article and Find Full Text PDFARYA Atheroscler
January 2024
Cardiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran,Iran.
Background: Necrotizing fasciitis is a life-threatening soft tissue infection characterized by rapid tissue necrosis, often leading to sepsis and multisystem organ failure. Necrotizing fasciitis can rarely occur as a post-procedural complication, particularly following cardiac catheterization or angiography. This case report presents the clinical presentation and management of a 64-year-old female with a history of chronic endocarditis and valvular involvement who developed necrotizing fasciitis after femoral coronary angiography.
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