We characterized a collection of IMI-like-producing Enterobacter spp. isolates (n = 112) in France. The main clone corresponded to IMI-1-producing sequence type 820 E. cloacae subspecies cloacae that was involved in an outbreak. Clinicians should be aware of potential antimicrobial resistance among these bacteria.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11138976 | PMC |
| http://dx.doi.org/10.3201/eid3006.231525 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
We characterized a collection of IMI-like-producing Enterobacter spp. isolates (n = 112) in France. The main clone corresponded to IMI-1-producing sequence type 820 E.
View Article and Find Full Text PDFEfficacy of Human-Simulated Epithelial Lining Fluid Exposure of Meropenem-Nacubactam Combination against Class A Serine β-Lactamase-Producing in the Neutropenic Murine Lung Infection Model.
Antimicrob Agents Chemother
April 2019
Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA
Nacubactam is a novel, broad-spectrum, β-lactamase inhibitor that is currently under development as combination therapy with meropenem. This study evaluated the efficacy of human-simulated epithelial lining fluid ELF) exposures of meropenem, nacubactam, and the combination of meropenem and nacubactam against class A serine carbapenemase-producing isolates in the neutropenic murine lung infection model. Twelve clinical meropenem-resistant , , and isolates, all harboring KPC or IMI-type β-lactamases, were utilized in the study.
View Article and Find Full Text PDFPutative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying -Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore.
Antimicrob Agents Chemother
January 2018
Department of Medicine, National University of Singapore, Singapore.
Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing complex to determine the flanking regions of -type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The -type genes were all found on Xer-dependent integrative mobile elements (IMEX).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!