Background: All parts of the research community have an interest in understanding research impact whether that is around the pathways to impact, processes around impact, methods for measurement, describing impact and so on. This proof of concept study explored the relationship between research funding and research impact using the case studies submitted to the UK Research Excellence Framework (REF) exercise in 2014 as a proxy for impact.
Methods: The paper describes an approach to link the REF impact case studies with the underpinning research grants present in the Researchfish dataset, primarily using the publications captured in both datasets. Where possible the methodology utilised unique identifiers such as Digital Object Identifiers and PubMed ID's, and where this was not possible the funding information within each publication was used.
Results: Through this automated approach 21% of the non-redacted case studies could be linked to a specific research grant. Additional qualitative analysis was then done for unlinked REF impact case studies, which involved reading the document to identify additional information to make the linkage. This approach was taken on 100 REF impact case studies selected at random and resulted in only seven having no identifiable research grants funding associated. The linked research grants were analysed to identify characteristics that are more frequently associated with these grants, than non-linked ones.
Conclusions: This analysis did point to some interesting observations such as the grant funding linked to REF impact case studies are more likely to be longer, higher financial value, have more publications and be more collaborative (amongst other characteristics). These findings should be used with caution at present and not be over interpreted, this is due to the sample size for this proof of concept study and some potential limitations on the data which were not addressed at this stage.
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http://dx.doi.org/10.12688/f1000research.74374.3 | DOI Listing |
BMC Bioinformatics
January 2025
Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China.
Background: MicroRNAs (miRNAs) are pivotal in the initiation and progression of complex human diseases and have been identified as targets for small molecule (SM) drugs. However, the expensive and time-intensive characteristics of conventional experimental techniques for identifying SM-miRNA associations highlight the necessity for efficient computational methodologies in this field.
Results: In this study, we proposed a deep learning method called Multi-source Data Fusion and Graph Neural Networks for Small Molecule-MiRNA Association (MDFGNN-SMMA) to predict potential SM-miRNA associations.
Geroscience
January 2025
The Jackson Laboratory, Bar Harbor, ME, USA.
Analysis of preclinical lifespan studies often assume that outcome data from co-housed animals are independent. In practice, treatments, such as controlled feeding or putative life-extending compounds, are applied to whole housing units, and as a result, the outcomes are potentially correlated within housing units. We consider intra-class (here, intra-cage) correlation in three published and two unpublished lifespan studies of aged mice encompassing more than 20,000 observations.
View Article and Find Full Text PDFMycopathologia
January 2025
Teikyo University Institute of Medical Mycology (TIMM), 359 Otsuka, Hachioji, Tokyo, 192-0395, Japan.
We describe a novel Malassezia species named Malassezia polysorbatinonusus, isolated from a Japanese patient with seborrheic dermatitis. The internal transcribed spacer (ITS) region of the isolate (LSEM 4845) were only 94.7% identical to those of M.
View Article and Find Full Text PDFSci Rep
January 2025
Advanced Power and Energy Center (APEC), Electrical Engineering Department, Khalifa University, Abu Dhabi, UAE.
Although detailed analytical models for droop-controlled microgrids are available, they are computationally complex and do not consider real-time variations in microgrid parameters and operating conditions. This paper proposes Kurtosis-Estimation of Signal Parameters via Rotational Invariance Technique (ESPRIT) to identify the dominant modes in droop-controlled inverter-based microgrids (IBMGs) using local real-time measurements. In the proposed approach, a short-duration small disturbance is applied to the selected DG's active power droop gain, and then, the system's dominant modes are estimated from its local measurements.
View Article and Find Full Text PDFContact Dermatitis
January 2025
Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
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