Objective: To explore the clinical effect of percutaneous pedicle screw anchored vertebral augmentation(PPSAVA) in the treatment of asymptomatic Kümmell disease without neurological symptoms.
Methods: The clinical data of 20 patients with Kümmell disease without neurological symptoms treated with PPSAVA in our hospital from January 2019 to December 2021 were analyzed retrospectively, including 5 males and 15 females, aged 56 to 88 (74.95±9.93) years old. and the course of disease was 7 to 60 days with an average of (21.35±14.46) days. All patients were treated with PPSAVA. The time of operation, the amount of bone cement injected and the leakage of bone cement were recorded. The visual analogue scale(VAS), Oswestry disability index(ODI), vertebral body angle(VBA), anterior edge height and midline height of vertebral body were compared among the before operation, 3 days after operation and during the final follow-up. The loosening and displacement of bone cement were observed during the final follow-up.
Results: All the 20 patients completed the operation successfully. The operation time was 30 to 56 min with an average of (41.15±7.65) min, and the amount of bone cement injection was 6.0 to 12.0 ml with an average of (9.30±1.49) ml. Bone cement leakage occurred in 6 cases and there were no obvious clinical symptoms. The follow-up time was 6 to 12 months with an average of (8.43±2.82) months. The VBA, anterior edge height and midline height of of injured vertebral body were significantly improved 3 days after operation and the final follow-up(<0.05), and the VBA, anterior edge height and midline height of of injured vertebral body were lost in different degrees at the final follow-up (<0.05). The VAS and ODI at 3 days after operation and at the final follow-up were significantly lower than those at preoperatively(<0.05), but the VAS score and ODI at the final follow-up were not significantly different from those at 3 d after operation(>0.05). At the last follow-up, no patients showed loosening or displacement of bone cement.
Conclusion: PPSAVA is highly effective in treating Kümmell disease without neurological symptoms, improving patients' pain and functional impairment, and reducing the risk of cement loosening and displacement postoperatively.
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http://dx.doi.org/10.12200/j.issn.1003-0034.20220829 | DOI Listing |
Cureus
December 2024
Department of Orthopaedic Surgery, The Jikei University School of Medicine, Tokyo, JPN.
Osteoporotic vertebral fractures (OVFs) in elderly patients pose challenges due to bone destruction and surgical risks. This case report describes a minimally invasive approach using calcium phosphate cement (CPC) vertebroplasty and short fusion with cement augmentation of pedicle screws (CAPS) in a 91-year-old woman with severe OVF. The patient underwent CPC vertebroplasty at L1 and CAPS fixation at T12-L2, followed by osteoporosis medication.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Endodontics, Faculty of Oral and Dental Medicine, Egyptian Russian University, Badr City, Egypt.
Background: Disinfection of the root canal system is a challenge to all clinicians, calcium hydroxide Ca(OH) one of the most popular intracanal medications used for this purpose, has some unwanted effects on dentine. This study aimed to investigate the antibiofilm effect of Nanochitosan (CSNPs) and Calcium hydroxide Ca(OH) intra canal medications and their effect on the microhardness and chemical structure of radicular dentine.
Methodology: A total of 52 extracted human mandibular premolars were used.
The Aim Of The Study: Was to elaborate and assess biocompatible compositions based on oligocarbonate methacrylate filled with hydroxyapatite.
Materials And Methods: The manufacturing methods of the compositions are considered, and their polymerization ability, strength and elastic properties are evaluated.
Results: The highest values of hardness and elasticity were found in the composition containing 0.
Front Cell Infect Microbiol
January 2025
Department of Orthopedics, Fuyang City People's Hospital, Fuyang, China.
Objective: The purpose of this study was to investigate the clinical efficacy of antibiotic-loaded bone cement (ALBC) combined with Negative pressure wound therapy (NPWT) aspiration technique in the treatment of multidrug-resistant diabetic foot ulcers (MDRO-DFUs).
Methods: A retrospective analysis of the clinical data of 80 patients with MDROs-DFU who were used Vacuum sealing drainage (VSD) as NPWT excipient and met the inclusion criteria from January 2019 to January 2024 at our hospital. Patients were divided into an experimental group and a control group, with 40 cases in each.
World Neurosurg
January 2025
Department of Orthopaedics, Binhai Hospital of Tianjin Medical University General Hospital, Tianjin 300480, China.
Background: This meta-analysis was conducted to compare the efficacy and safety of vertebral augmentation (VA) plus pedicle screw fixation (PSF) with VA for treating osteoporotic thoracolumbar fractures (OTLFs).
Methods: A comprehensive search was conducted in PubMed, Embase, Cochrane Library and China National Knowledge Infrastructure (CNKI) to identify studies comparing PSF+VA with VA for treating OTLF. The primary outcomes were operation time, blood loss, length of stay, visual analogue scale (VAS) score, Oswestry disability index (ODI), Cobb angle, anterior vertebral height (AVH), bone cement leakage, secondary fracture and other adverse events.
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