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Timing of Radiographic Healing for Distal Femur Fractures Treated With Intramedullary Nails.
J Orthop Trauma
December 2024
University of California, Los Angeles, CA.
Article Synopsis
- This study evaluated modified Radiographic Union Scale for Tibia (mRUST) scores over time in patients with distal femur fractures treated with intramedullary nails, to identify factors influencing healing and possible reoperation.
- Conducted in ten Level I Trauma Centers, the research included 155 fractures from 152 patients, focusing on mRUST scores at 3, 6, and 12 months post-surgery, with the primary goal of finding predictors for union timing.
- Results showed that a 3-month mRUST score of ≤8 indicated a higher chance of reoperation, and factors such as tobacco use and open fractures correlated with delayed healing times.
Background: Chronic stress causes harmful physiological responses that yield increased inflammation and subsequent health conditions. Stress is an important measure among minoritized populations who face social situations that predispose risk to developing mental health problems. Hair and fingernail cortisol have been studied as retrospective measures of chronic stress and to demonstrate biological response to social situations.
View Article and Find Full Text PDFOverview of chromatin regulatory processes during surface ectodermal development and homeostasis.
Dev Biol
November 2024
Black Family Stem Cell Institute, Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:
The ectoderm is the outermost of the three germ layers of the early embryo that arise during gastrulation. Once the germ layers are established, the complex interplay of cellular proliferation, differentiation, and migration results in organogenesis. The ectoderm is the progenitor of both the surface ectoderm and the neural ectoderm.
View Article and Find Full Text PDFExploring self-care practices of African American informal kinship caregivers.
Child Fam Soc Work
February 2024
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
African American caregivers providing informal kinship care are vulnerable to chronic stress. Research has indicated stress increases individuals' risk for many adverse physical and mental health outcomes, including cardiovascular disease, Alzheimer's disease and depression. Given the adverse outcomes related to stress, identifying mechanisms to help these caregivers lower and manage their stress is critical to their overall health and well-being.
View Article and Find Full Text PDFResidential proximity to toxic metal-emitting industrial sites and toenail metal concentrations in a United States-wide prospective cohort.
Environ Res
October 2024
Epidemiology Branch, Division of Intramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. Electronic address:
Background: Industrial facilities across the United States (US) release millions of pounds of toxic chemicals, including metals. Exposure to toxic metals has been associated with adverse health outcomes, but there is limited evidence on the association between living near metal-releasing facilities and the body burden of emitted compounds.
Objective: To investigate the association between residential proximity to toxic metal-emitting industrial facilities and toenail metal concentrations and to evaluate whether associations differed by race.
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