AI Article Synopsis
- Diffuse midline glioma, H3K27-altered, is a new subtype of diffuse astrocytoma, marked by a specific histone mutation (H3K27M).
- This rare and severe condition primarily affects children and has a particularly poor prognosis.
- The case reported involves a 30-year-old woman diagnosed with this type of glioma, highlighting its occurrence outside the typical pediatric demographic.
Article Abstract
Diffuse midline glioma, H3K27-altered, is a relatively new entity, characterized by H3K27M histone mutation. This rare pediatric disease with severe prognosis has recently been identified as a new subtype of diffuse astrocytoma due to major breakthrough in histopathological and molecular characterization of gliomas. We report a case of H3K27-altered diffuse midline glioma in a 30-year-old woman.
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| http://dx.doi.org/10.1097/RLU.0000000000005246 | DOI Listing |
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